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138 items found for "DRY/DRF/DRL motif"
Posts (57)
- The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid Receptor
Studies have indicated that transmembrane helix 7 (TMH7) and the highly conserved NPXXY motif can be
- PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
Here, we demonstrate identification of a pleckstrin-homology (PH)-binding motif within PAR4, critical lead backbone cyclic peptide, was selected out of a mini-library, directed toward PAR2&4 PH-binding motifs
- Posttranslational modifications in GPCR internalization
GPCR internalization undergoes a series of strict regulations, especially by posttranslational modifications
Other Pages (81)
- Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors
two datasets, a mutation enrichment in cancer patients was observed among class-specific conserved motifs in GPCRs such as the Class A "DRY" motif. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Expanding role of CXCR2 and therapeutic potential of CXCR2 antagonists in inflammatory diseases and cancers
CXCR2 antagonists in inflammatory diseases and cancers Published date March 15, 2023 Abstract " C-X-C motif GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
GPCR News and get weekly notifications about the GPCR field Share < Previous Next >