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Nguyen ,  Ziaurrehman Tanoli ,  Saad Hassan , Umut Onur Özcan ,   Jimmy Caroli ,   Albert J Kooistra ,   David E Gloriam ,   Alexander S Hauser GPCRdb in 2025: adding odorant receptors, data mapper, structure similarity Taracena Herrera , Søren N Andreassen ,   Jimmy Caroli ,   Albert J Kooistra , Gáspár Pándy-Szekeres ,   David E Gloriam , et al.

neuroprotective mechanism involving interaction between neurotrophic factor-α1 (NF-α1/carboxypeptidase E,

David Gloriam and Dr. Albert Kooistra.

David Gloriam , Dr.

This week's highlight includes congrats to: Clementine E Philibert and Mikel Garcia-Marcos for their spatial, temporal and ligand bias of G protein-coupled receptors Antonios Drakopoulos, Peter Gmeiner, Davide

Lukas Grätz, David Gloriam, and Gunnar Schulte’s research on Unveiling pathway selectivity in Frizzleds

E, 2002). E., et al. 2008). E., et al. 2008).

David Gloriam and his team present GproteinDb in 2024 Are you looking to hire?

This week's highlight includes congrats to: David A Cooper, David Minh, et al., for their research on

., Rands, E., Diehl, R. E., Mumford, R. A., Slater, E. E., Sigal, I. S., Caron, M.

., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F. M., Manglik, A., Hu, J., Hu, K., Eitel, K., Hübner, H., Pardon, E., Valant, C., Sexton, P. M., Dukkipati, A., Feinberg, E. N., Angelini, A., Waghray, D., Dror, R. O., Ploegh, H. D., Tworak, A., Watanabe, K., Pardon, E., Steyaert, J., Kandori, H., Katayama, K., Kiser, P.

Matthew E. on Friday, October 7th at 1 PM ET.

GPCR phosphorylation patterns, which influence their conformational states and functions (Matthees, E. E. et al. 2022). E. et al. 2017). evolutionary conservation of both isoforms from fish to mammals indicates their non-redundant roles (Gurevich, E. determining the formation of protein complexes and their functions within specific tissues (Matthees, E.

That is, besides classical ligands, a great number of bivalent ligands (i. e. aiming on two distinct

E., Vitale, R. M., Tomašević, N., ... & Carreira, E. M. (2024).

E., & Puthenveedu, M. A. (2021). Compartmentalized GPCR Signaling from Intracellular Membranes. E., Healy, M. D., & Collins, B. M. (2019). E., French, R. P., Lowy, A. M., & Murray, F. (2018).

showed spontaneously fluctuating Ca levels from approximately normal to near fatally high ranges, (e)

reveals unexpected differences in downstream pathway activation Chiara D Mancinelli, Joshua Levitz, David

E. Cardona et al. 2008). E. Cardona et al. 2008).

José Labandeira-García , Rafael Franco Endomembrane GPCR signaling: 15 years on, the quest continues Davide

Burger , Arthur Christopoulos , David M.

., Mehrota, E., Grimes, P. R., ... & Manglik, A. (2024).

This Week’s Highlights: G protein-coupled receptor (GPCR) pharmacogenomics Miles D Thompson , David

Physiology or Medicine was awarded jointly to Ragnar Arthur Granit, Haldan Keffer Hartline, and George David E. Nobel Prize: Three Named for Medicine, Physiology Award. Ekaterini Tiligada, C., Tiligada, E. & Ennis, M.

Terence E.

Structure-guided design of a peripherally restricted chemogenetic system Hye Jin Kang , Brian E Krumm

molecular dynamics simulations Leukotriene B4 receptor 1 (BLT1) activation by leukotriene B4 (LTB4) and E

Encoded Fluorescent Indicators Design of an effective small expression tag to enhance GPCR production in E.