Search Results
231 items found for "David Reiner-Link"
- Ep 118 with Dr. David Sykes
David Sykes About Dr. David Sykes " David Andrew Sykes, BSc Hons Pharmacology, MSc Molecular Biology and Biochemistry, PhD David has over 20+ years of experience working in a drug discovery environment mainly in a specialist In 2014 David joined the University of Nottingham and began a part-time PhD in Molecular Pharmacology David Sykes on the web Veprintsev Lab ResearchGate LinkedIn Dr.
- Ep 143 with Dr Davide Calebiro
Davide Calebiro About Dr. Davide Calebiro "Davide Calebiro is Chair of Molecular Endocrinology and Wellcome Trust Senior Research Davide’s work has been published in prestigious scientific journals such as Nature, Cell, New England Davide Calebiro on the web University of Birmingham Twitter Google Scholar LinkedIn Dr.
- Ep 33 with Dr. David E. Gloriam
David E. Gloriam About this episode David Gloriam is a Professor in Computational Receptor Biology at the University David obtained his Ph.D. from Uppsala University in Sweden where he worked on the bioinformatic identification Join me a learn more about David’s work, his career trajectory, and GPCRdb. Dr. David E. Gloriam on the web LinkedIn ResearchGate Twitter Google Scholar Computation Receptor Biology- Gloriam
- Ep 52 with Dr. Benjamin Myers
operate within the primary cilium, a tiny antenna-shaped structure at the cell surface with critical links Prior to that, Ben received his Ph.D. from UCSF in 2008, where he worked with David Julius on the structure
- Targeting adenosine signaling for immuno-oncology
recent work on adenosine-producing ectonucleotidases and adenosine signaling and discuss unexpected links Authors and Affiliations John Stagg , David Allard . University of Montréal Québec Cancer Consortium The University of Montreal Hospital Research Centre Pubmed LinkedIn
- Ep 124 with Gáspár Pándy-Szekeres
Gáspár Pándy-Szekeres " After a BSc in biology and a MSc in bioinformatics, I have been working in David free time I like to play the guitar, sing and play board games. " Gáspár Pándy-Szekeres on the web LinkedIn
- Ep 38 with Dr. Alexander S. Hauser
During his Ph.D. with David Gloriam at the Department of Drug Design and Pharmacology in Copenhagen, Hauser on the web Twitter ResearchGate University of Copenhagen LinkedIn Google Scholar Dr.
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
Authors Karthik Nath, Tala Shekarkhand, David Nemirovsky, Andriy Derkach, Bruno Almeida Costa, Noriko Nishimura, Tasmin Farzana, Colin Rueda, David J Chung, Heather J Landau, Oscar B Lahoud, Michael Scordo
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Usage of Lorazepam, which has off target agonism of GPR68, is linked to worse clinical outcomes for a titer glo, were used to demonstrate sensitivity to GPR68 inhibition in twelve immortalized and PDX GBM lines To determine GPR68 inhibition's mechanism of cell death we use DAVID pathway analysis of RNAseq. we show that blocking GPR68 signaling results in robust cell death in all thirteen glioblastoma cell lines We use U87 and U138 glioblastoma cell lines to show how selective induction of ferroptosis occurs in
- Distinct Activation Mechanisms of CXCR4 and ACKR3 Revealed by Single-Molecule Analysis of their Conformational Landscapes
Much of the conformational heterogeneity of ACKR3 is linked to a single residue that differs between Authors Christopher T Schafer, Raymond F Pauszek 3rd, Martin Gustavsson, Tracy M Handel, David P Millar
- Protease-Activated Receptor-1 IgG Autoantibodies in Patients with COVID-19
Szandor Simmons, Wolfgang M Kuebler, Martin Witzenrath, Lajos Markó, Kai Jakobs, Marianna Puccini, David
- Ep 123 with Dr. Lukas Grätz
Lukas Grätz "After a BSc in biology and a MSc in bioinformatics, I have been working in David Gloriam's
- Ascitic Shear Stress Activates GPCRs and Downregulates Mucin 15 to Promote OvarianCancer Malignancy
Jackson, Ishwarya Venkata Narayanan, Fulei Wuchu, Minal Nenwani, Zachary Fischer, Alec Sunshine, Zequan Lin , Linh Tran, Deepak Nagrath, Mats Ljungman, Katherine Maturen, Analisa DiFeo, David Nordsletten Tags
- Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to Investigate Metabolic Disease Pathophysiology
David Siderovski and Vincent Setola (2014-2019). minimize side effects for diet-induced metabolic diseases. " Josh Gross on the web Pubmed Google Scholar LinkedIn
- Ep 100 with Dr Caron Tribute Part 1
David Sibley (1988) Memories our panelists shared with us Thanks for listening to this podcast episode
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
Authors Xiaodi Hu, David S Hoffmann, Mai Wang, Lars Schuhmacher, Maria C Stroe, Birgit Schreckenberger
- Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ
DAVID Functional enrichment analysis in the TGFβ and IFNγ dataset revealed association of genes with
- Expression prevalence and dynamics of GPCR somatostatin receptors 2 and 3 as cancer biomarkers beyond NET: a paired immunohistochemistry approach
Authors Mor Oron-Herman , David Kirmayer , Amelie Lupp , Stefan Schulz , Genady Kostenich , Michel Afargan
- In Silico Design of Novel RGS2-Galpha-q Interaction Inhibitors with Anticancer Activity
Authors Adam Bair, Natalie Printy, So Hee Choi, Joshua Wilkinson, Joseph O'Brien, Brian Myers, David
- Bispecific antibodies targeting BCMA or GPRC5D are highly effective in relapsed myeloma after CAR T-cell therapy
Holderried, Roland Fenk, Fabian Müller, Natalia Tovar, Aina Oliver-Cáldes, Kristin Rathje, James A Davis , David Fandrei, Vladan Vucinic, Soraya Kharboutli, Ben-Niklas Baermann, Francis Ayuk, Uwe Platzbecker
- DANGER Signals Activate G-Protein Receptor Kinases Suppressing Neutrophil Function and Predisposing to Infection After Tissue Trauma
Authors Hyo In Kim , Jinbong Park , David Gallo , Sidharth Shankar , Barbora Konecna , Yohan Han , Valerie
- G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions
Oncology and Immunology G protein-coupled receptors: A target for microbial metabolites and a mechanistic link
- Session VI | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
About Yimin Zou "I received Ph.D from University of California at Davis and San Diego in 1995 and then We initially tested the ADC using in vitro WST-8 viability assays in human GBM cell lines and cell types Dimitris Placantonakis on the web Placantonakis Lab Google Scholar LinkedIn Adhesion G protein-coupled Mosharov1,2,4, David Sulzer1,2,4, Christoph Kellendonk1,2, and Jonathan A. Nicole Perry-Hauser on the web LinkedIn Research Gate Pubmed Dr.
- Session VIII * | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Auger, Helen Strutt, David Strutt" About Tobias Langenhan "1997-2004: Medical school and Dr. med. : Professor and Chair in Biochemistry (Leipzig, Germany)" Tobias Langenhan on the web Langenhan Lab LinkedIn
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
< GPCR News < GPCRs in Oncology and Immunology Functional Assessment of Cancer-Linked Mutations in Sensitive Identified intolerant residues with reported cancer-linked mutations RGS14-R173C/H and RGS4-K125Q/E126K These findings show that 3DMTR identified intolerant residues that overlap with cancer-linked mutations : Human genetic variant/mutation information has expanded rapidly in recent years, including cancer-linked ratio (3DMTR) to define regions of genetic intolerance in RGS proteins and prioritize which cancer-linked
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
Authors Brian Kim , Marc E Rothenberg , Xin Sun , Claus Bachert , David Artis , Raza Zaheer , Yamo Deniz
- Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation
endogenous role of this pro-resolving receptor in modulating macrophage biology using a novel mouse line This was linked with an increased inflammatory response in the Gpr101 deficient animals and a reduced These observations were linked with a marked dysregulation in peritoneal lipid mediator concentrations
- Ep 146 with Dr Michael Feigin
David Tuveson at CSHL where he participated in the development of an organoid system for the culture Michael Feigin on the web Roswell Park Feigin Lab Google Scholar LinkedIn Twitter Dr.