on Constitutive internalisation of EP2 differentially regulates G protein signalling Ethan Dintzner, Demet Araç, et al. for their work on The far extracellular CUB domain of the adhesion GPCR ADGRG6/GPR126 is

Araç, D., et al., A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

expression was induced in fibrotic liver and kidney, but suppressed in endothelial cells. cGAS genetic deletion Meanwhile, cGAS deletion upregulated profibrotic Yes-associated protein (YAP) signaling in endothelial

eosinophilia in the mouse model of ECRS with myeloid cell‐specific autophagy‐related gene 7 ( Atg7 ) deletion

Deletion of phospholipase Cβ3 (PLCβ3), or selective inhibition of Gβγ regulation of PLCβ3, enhances the

found that inhibition of GRP78-ATF6-CHOP apoptosis signaling improved ESS symptoms, and the targeted deletion

Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses