August 2022 A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology

., Choi, H. J., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. H., Pautsch, A., Steyaert, J., Weis, W. I., & Kobilka, B. K. (2011). M., Manglik, A., Hu, J., Hu, K., Eitel, K., Hübner, H., Pardon, E., Valant, C., Sexton, P. O., Ploegh, H. L., & Garcia, K. C. (2015). Structural biology. D., Tworak, A., Watanabe, K., Pardon, E., Steyaert, J., Kandori, H., Katayama, K., Kiser, P.

peroxidase enzyme that catalyzes the oxidation of specific substrates in the presence of hydrogen peroxide (H When AUR is oxidized by APEX2 in the presence of H 2 O 2 , it produces a fluorescent product that can

RT-qPCR results showed that the gene expression levels of GPRC5A at different time point (2, 6, 12, 24 h) group (0.004±0.000, 0.004±0.000, 0.002±0.000, 0.007±0.000) (all P<0.001), respectively, and peaked at 6 h. Authors Y H Hu , L L Shang , S H Ge Source Contribute to the GPCR News Coming soon Become a Contributor

Identified intolerant residues with reported cancer-linked mutations RGS14-R173C/H and RGS4-K125Q/E126K Authors Carolina Montañez-Miranda , Riley E Perszyk , Nicholas H Harbin , Jennifer Okalova , Suneela

He has published more than 800 scientific publications, with an H-index of 115.