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and the intracellular helix 8 move outward from the receptor core to make room for the G-protein (Lu, Zhao namely CCL15L (residues 26-92) and CCL15M (residues 27-92), while the third structure lacks a ligand (Shao conformational change of Y2917.43 tilted toward TM2, a model supported by mutagenesis experiments (Shao

Zhao et al. 2019). Zhao et al. 2019) together with confocal fluorescence microscopy.

Zhao, P., et al., Activation of the GLP-1 receptor by a non-peptidic agonist. 

For example, OR4M1 was proposed to interfere with aberrant tau hyperphosphorylation (Zhao W. et. al 2013

Zhan-Guo Gao, Mansour Haddad, and Kenneth A Jacobson for their work on A2B adenosine receptor signaling

Week’s Highlights: SNX9 family mediates βarrestin-independent GPCR endocytosis Valeria Robleto , Ya Zhuo

Through developing a high-resolution method, Hao Chen et al. directly visualized the fusion of vesicles

Highlights: Congrats to: Ya-Tzu Li , our notable contributor, for her superb undergrad paper along with Hao-Jen