GPCR) pharmacogenomics Miles D Thompson , David Reiner-Link , Alessandro Berghella , Brinda K Rana , G Enrico Rovati , Valerie Capra , Caroline M Gorvin , Alexander S Hauser Calcineurin-fusion facilitates cryo-EM

We hypothesized that somatic mutations in tumor samples may not be enriched within a single gene but Individual cancer types were enriched for highly impactful, recurrent mutations at selected cognate positions

Moreover, in the presence of very high levels of HH, the second effect of FU leads to the local enrichment

) and weighted correlation network analysis (WGCNA) were performed using R software, and functional enrichment

Affinity proteomics revealed that in the interactome of VLGR1, molecules are enriched that are associated

modeling and the 1.5-μs molecular dynamics data presented in the current study are expected to further enrich

physicochemical aspects of ligand binding at the receptor-lipid interface and suggest a compound library enriched

Go enrichment analysis indicated that the mechanism of KXS in treating depression was involved in the

However, acute in vivo stimulation of endogenous Gs-coupled receptors enriched in SKM has only a limited

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development of biased ligands, which promote the engagement of the receptor with a certain effector, thus enriching

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Selection of the libraries typically leads to the isolation of several hundred candidate hits, enriched