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2 items found for "Enterococcus"
- Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis
< GPCR News < GPCRs in Oncology and Immunology Enterococcus-derived tyramine hijacks α2A-adrenergic receptor Through PRESTO-Tango screening, we demonstrate that tyramine, primarily produced by Enterococcus via Using an engineered tyrDC-deficient Enterococcus faecalis strain and intestinal epithelial cell-specific Adra2a knockout mice, we show that Enterococcus-derived tyramine suppresses ISC proliferation, thereby Wei , Kaiguang Zhang , Dan Cao , Rongbin Zhou , Sheng Wang , Xinyang Song , Shu Zhu , Wen Pan Tags Enterococcus
- A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages
Cellulosimicrobium and a reduced proportion of Escherichia, whereas CD patients showed a decreased abundance of Enterococcus
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