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16 items found for "GPR97"
Posts (10)
- Mechanistic Understanding of the Palmitoylation of Go Protein in the Allosteric Regulation of...
Understanding of the Palmitoylation of Go Protein in the Allosteric Regulation of Adhesion Receptor GPR97 The orphan receptor GPR97, activated by glucocorticoid stress hormones, is a prototypical aGPCR. Hence, we performed extensive large-scale molecular dynamics (MD) simulations of the GPR97-Go complex conformational landscapes analyzed by Markov state models revealed that the overall conformation of GPR97 and increase the affinity of the ligand for GPR97.
- 📰 GPCR Weekly News - January 9 to 15, 2023
GPR97 deficiency ameliorates renal interstitial fibrosis in mouse hypertensive nephropathy.
- 📰 GPCR Weekly News, May 29 to June 4, 2023
GPCRs in Cardiology, Endocrinology, and Taste GPR97 deficiency ameliorates renal interstitial fibrosis
Other Pages (6)
- GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway
< GPCR News < GPCRs in Oncology and Immunology GPR97 depletion aggravates imiquimod-induced psoriasis In this research, our team allocated GPR97 depletion (GPR97-/-), GPR97 conditional depletion on dendritic cell (DC-cKO), and keratin 14-conditional knockout (K14-cKO) mice models to explore the function of GPR97 It was found that significantly aggravated psoriasis-like lesion in GPR97-/- mice. Particularly, we found that level of NF-κB p65 was increased in GPR97-/- DCs and BDP could inhibit p65
- Student Flash Presentations
Expressed Gpr116 (Adgrf5) Transcript Variants in Mouse Kidney Hailey Steichen Elucidating The Role Of GPR97 Hailey Steichen on the web Zaidman Physiology Lab Elucidating The Role Of GPR97/ADGRG3 In Neutrophil
- Session I
Recently, we have elucidated the high-resolution structures of GPR97 transitioning from its inactive