Search Results
9 items found for "GRK"
- Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
type-specific functions Published date November 1, 2022 Abstract G-protein coupled receptor kinases (GRKs However, there is growing evidence that GRKs can also control cellular functions beyond GPCR regulation Immune cells commonly express two to four members of the GRK family (GRK2, GRK3, GRK5, GRK6) simultaneously In particular, we are missing comprehensive studies comparing the role of this GRK interplay for (a) To address this issue, we generated mouse models of single, combinatorial and complete GRK knockouts
- Ep 130 with Dr. Richard Premont
initial project to identify and clone taste receptors was unsuccessful, but led to the identification of GRK5 and continued focus on GRKs (particularly GRKs 4,5,6) and arrestins as GPCR regulators and as mediators regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK
- Ep 131 with Dr. Richard Premont
initial project to identify and clone taste receptors was unsuccessful, but led to the identification of GRK5 and continued focus on GRKs (particularly GRKs 4,5,6) and arrestins as GPCR regulators and as mediators regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK
- Ep 133 with Dr. Richard Premont
initial project to identify and clone taste receptors was unsuccessful, but led to the identification of GRK5 and continued focus on GRKs (particularly GRKs 4,5,6) and arrestins as GPCR regulators and as mediators regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK
- Ep 132 with Dr. Richard Premont
initial project to identify and clone taste receptors was unsuccessful, but led to the identification of GRK5 and continued focus on GRKs (particularly GRKs 4,5,6) and arrestins as GPCR regulators and as mediators regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK
- Structure-based discovery of functionally selective 5-HT1A receptor agonists
has been spokesman of the Research Training Group "Medicinal Chemistry of Selective GPCR Ligands" (GRK
- Ep 152 with Dr Arthur Christopoulos
They discussed various modulatory elements, such as RAMPs, G proteins, and GRKs, with Arthur recounting
- miR-19a may function as a biomarker of oral squamous cell carcinoma (OSCC) by regulating the signaling pathway of miR-19a/GRK6/GPCRs/PKC in a Chinese population
as a biomarker of oral squamous cell carcinoma (OSCC) by regulating the signaling pathway of miR-19a/GRK6 Wang , Danhua Ma , He Zhang , Jiayan Fan , Hongyan Gao , Xinyu Xia , Wei Wu , Yuyuan Shi Tags GPCR , GRK6
- Unveiling Non-Canonical Functions for Gαq Signaling Pathways
Ribas has also described a new protective role of G protein-coupled receptor kinase 2 (GRK2), a known