Oncogenic Potential and Is Markedly Upregulated in Hepatocellular Carcinoma "Hepatocellular carcinoma (HCC ) is at the forefront of the global cancer burden, and biomarkers for HCC are constantly being sought role of RGS20 as a potential prognostic marker in 28 different cancer types with special emphasis on HCC associated with some important clinical parameters such as alpha-fetoprotein and tumor grade in the HCC potential and is markedly upregulated in HCC patients.

Our previous study indicated that ARBB1 (arrestin beta 1) promotes hepatocellular carcinogenesis (HCC However, the role of ARRB1 in HBx-related HCC remains unclear. Our results demonstrate that ARRB1 plays a critical role in HBV-related HCC via modulating autophagy and the CDKN1B-CDK2-CCNE1-E2F1 axis and indicate that ARRB1 may be a potential therapeutic target for HCC factor 1; FBS: fetal bovine serum; GPCRs: G protein-coupled receptors; GST: glutathione S-transferase; HCC

Insights into GPCR Function Studying allosteric regulation of chemokines and antagonists using a nanoscale hCCR3

that transforming growth factor-α (TGF-α) induces the migration of human hepatocellular carcinoma (HCC This study aims to determine whether Gβγ subunits regulate the TGF-α-induced migration of HCC HuH7 cells results strongly suggest that Gβγ subunits act as positive regulators in TGF-α-induced migration of HCC