which contains the hormone-binding site and is linked to the transmembrane domain by the hinge region (HR How this HR is involved in hormone binding and signal transduction is still an open question. A major rearrangement of the HR seems implausible due to the tight arrangement and fixation by disulfide

Meiling Lim TRUQAP™ (capivasertib) plus fulvestrant approved in the US for patients with advanced HR-positive

August 5th to 11th, 2024 GPCR Activation and Signaling Pharmacological characterization of the zebrafish Hrh2a

Docking analysis of rs35106420, harbored in the ADGLR3-hormone receptor domain (HRM, a common extracellular domain of the secretin-like GPCRs family), showed that HRM interacts with the Glucose-dependent insulinotropic