Search Results
7 items found for "HRS"
- PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in ovarian cancer
Low PAXIP1-AS1 expression predicted a poorer overall survival (OS) (HR: 0.71; 95% CI: 0.55-0.92; P = 0.009), progression free interval (PFS) (HR: 1.776; 95% CI: 1.067-2.955; P = 0.001) and disease specific survival (DSS) (HR: 0.67; 95% CI: 0.51-0.89; P = 0.006). PAXIP1-AS1 expression (HR: 0.711; 95% CI: 0.542-0.934; P = 0.014) was independently correlated with PFS was associated with immune infiltration. low expression of PAXIP1-AS1 was correlated with poor OS (HR
- GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
GPR143 interacts with HRS (an ESCRT-0 Subunit) and promotes its association to cargo proteins, such as Je , Yang Hoon Huh , Sun-Young Kong , Taejoon Kwon , Pann-Ghill Suh , Young Chan Chae Tags GPR143 , HRS
- Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy
On multivariable analysis, hypogammaglobulinemia (hazard ratio [HR], 6.06; P = .044) and diagnosis of an early respiratory viral infection (HR, 2.95; P = .048) were independent risk factors for late respiratory
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
recipients had higher infection rates (IRR:2.27, 1.31-3.98, P = 0.004) and time to severe infection (HR During periods of non-neutropenia, CAR-T recipients had a lower risk (HR 0.44, 95%CI 0.21-0.93, P = 0.032
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
The Chateau Montebello is an exceptional venue, and is located 1 hr from Ottawa, or 1.5 hr from Montreal
- Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration
The roles of histamine and histamine receptor H1 (HRH1) in cancer pathogenesis remain controversial. Here, we show that HRH1 is widely expressed in various cancer cell lines and cancer tissues and that coexpression of CXCR4 and HRH1 is associated with poor prognosis in breast cancer. that endogenously express CXCR4 and HRH1 but not in cells deficient in CXCR4 or HRH1. of the CXCR4-HRH1 heteromer as a potential therapeutic target for anticancer therapy."
- Molecular docking and dynamics simulation studies uncover the host-pathogen protein-protein interactions in Penaeus vannamei and Vibrio parahaemolyticus
The P. vannamei-V. parahaemolyticus protein-protein interaction of Complex 1 (Ferritin-HrpE/YscL family