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Despite major advances in the field of pharmacological CVD treatments, particularly in the field of heart failure (HF) research, case numbers and overall mortality remain high and have trended upwards over differential domains of GRK2 to modulate both beneficial and deleterious signaling pathways in the heart

events driving the fibrotic response and the communications between fibroblasts and other cells in the heart

October 2022 "Systolic heart failure (HF) is a chronic clinical syndrome characterized by the reduction alterations that confer significant hormonal burden on the already compromised function of the failing heart receptor antagonists, which block the effects of angiotensin II (AngII) and aldosterone on the failing heart

Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure Published date April 1, 2023 Abstract " Aims: A causal link between non-ischaemic heart failure volumes, and myocardial structural properties were assessed by cardiac magnetic resonance imaging; right heart Tags Chronic non-ischaemic heart failure , Heart failure , Pathophysiology .

It turns out that it was signal transduction, and he worked on the signaling cascades involved in heart failure.

focus is on pulmonary arterial hypertension, a disease of the pulmonary arterioles that causes right heart failure, and he serves as co-director of the Duke Pulmonary Vascular Disease Center.