September 2022 A2B Adenosine Receptor Enhances Chemoresistance of Glioblastoma Stem-Like Cells under Hypoxia However, adenosine/MRPs-dependent chemoresistance under hypoxia has not been studied until now. Here, we show for the first time that MRP3 expression is induced under hypoxia through the A2B adenosine Hypoxia enhances MRP-dependent extrusion capacity and the chemoresistance of GSCs. Meanwhile, MRP3 knockdown decreases GSC viability under hypoxia.

hepatitis B virus; HBx: hepatitis B virus X protein; HMGB1: high mobility group box 1; HIF1A/HIF-1α: hypoxia

Targeted inhibition of the GRK2/HIF-1α pathway is an effective strategy to alleviate synovial hypoxia

EXS74539 Domain Therapeutics unveiled its 2023 women-men professional equality index Octant introduces Hypatia

Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration