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275 items found for "HyunGee Ha"
- G Protein-coupled Receptor-mediated Membrane Targeting of PLCγ2 is Essential for Neutrophil Chemotaxis
neutrophil chemotaxis. " Authors Xuehua Xu , Xi Wen , Smit Bhimani , Amer Moosa , Dustin Parsons , HyunGee Ha , Tian Ji .
- Ep 42 with Dr. Randy Hall
Randy Hall About Dr. Over the past two decades, his lab has published numerous groundbreaking findings shedding light on the Most recently, his lab has made a number of seminal contributions to understanding the signaling, regulation Randy’s lab has a special interest in studying disease-associated mutations to human GPCRs that perturb Randy has received a number of research prizes, including the PhRMA New Investigator Award, the Distinguished
- Ep 91 with Dr. Oliver Hartley
Oliver Hartley About Dr. Oliver Hartley Oliver Hartley is VP for Drug Discovery at Orion Biotechnology . Since then Oliver has worked at the University of Geneva, where his research on peptide engineering and GPCR pharmacology has led to a series of high-profile publications and new intellectual property, and Oliver Hartley on the web LinkedIn Orion Biotechnology Dr.
- "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways
About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule "Have coupled receptors and receptor activity modifying proteins in vascular biology, the Caron laboratory has Caron has received numerous awards including a Burroughs Wellcome Fund Career Award in the Biomedical
- Ep 26 with Dr. Debbie Hay
Debbie Hay About this episode Dr. Debbie Hay is presently a professor at the Department of Pharmacology and Toxicology at the University She has gained experience from working in academia and at GSK as an industrial trainee. Debbie Hay on the web LinkedIn Wikipedia University of Otago University of Auckland Google Scholar Pubmed
- Ep 38 with Dr. Alexander S. Hauser
Hauser About Dr. Alexander S. Hauser Alexander is currently a postdoc as a member of the personalized medicine cluster in Copenhagen Alexander has a big interest in the integration of large biomedical data in genomics, structural biology Alexander had a research sabbatical with Madan Babu at the MRC Laboratory of Molecular Biology in Cambridge Hauser on the web Twitter ResearchGate University of Copenhagen LinkedIn Google Scholar Dr.
- Ep 73 with Dr. Aylin Hanyaloglu
Aylin Hanyaloglu About Dr. Aylin Hanyaloglu Dr. Aylin Hanyaloglu has been a Principal Investigator at Imperial College London since 2007. Hanyaloglu undertook her postdoctoral training at the University of California, San Francisco with Professor Aylin Hanyaloglu on the web LinkedIn Researchgate Twitter Imperial College London Elsevier Loop Dr.
- Unveiling Non-Canonical Functions for Gαq Signaling Pathways
Catalina Ribas, is currently an Associate Professor at the University Autonomous of Madrid (UAM) and she has Molecular “Severo Ochoa” (UAM/CSIC) and belongs also to the Health Research Institute La Princesa, has During this period and her doctoral thesis, she has deepened the regulatory mechanisms of GPCR signaling In her postdoctoral period, she has participated in the identification and characterization of proteins Ribas' group has described a new interaction region in a cellular protein that has turned out to be very
- Ep 75 with Vaithish Velazhahan
His Ph.D. work has been focused on understanding the structure and activation of Class D fungal GPCRs He has developed novel tools and methodologies to study fungal GPCRs which allowed the determination This work has led to two first-authored manuscripts published in the journal Nature. Vaithish has been recognized with the MRC LMB's Max Perutz Prize for outstanding Ph.D. work and has been
- Ep 136 with Murat Tunaboylu & Ben Holland
podcast list Murat Tunaboylu & Ben Holland About Murat Tunaboylu "Murat Tunaboylu, Antiverse's CEO, has Mid-career, he has worked in finance and developed high-frequency trading systems. After switching to biotech, Murat has built cell imaging software and lab robots to accelerate cancer He has co-founded consultancy and biotech companies Svarlight and Antiverse. He then returned to information engineering and has been working in machine learning for nearly 10 years
- Ep 54 with Dr. JoAnn Trejo
Trejo’s research has focused on PAR1, which has important functions in hemostasis, thrombosis, inflammation She has made numerous important discoveries related to the mechanisms that control PAR1 signaling and Trejo has been continuously funded by the NIH for >20 years and was a recipient of the prestigious American is the recognized expert on protease-activated receptors, particularly PAR1, and over the years she has Trejo has presented her studies at 52 national/international meetings and 66 academic seminars across
- Ep 60 with Dr. Josephine (Pina) Cardarelli
., based in South Korea, has recently been named President of GPCR Therapeutics, USA, a newly incorporated She was a participant in numerous due diligence (anti-CXCL8 mAb) and has managed external collaborations the type I interferon-alpha receptor project, licensed to AstraZeneca (Saphnelo™ Anifrolumab) that has She has extensive experience working with Biologics, and Antibody Drug Conjugates as well as experience She has also authored forty-six peer-reviewed publications. Dr.
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
He has focussed on developing a comprehensive map of ovarian cancer essential genes using whole genome This approach has provided insight into novel drivers resulting from the widespread gene copy number A second area of interest has been the elucidation of the molecular basis for a rare autosomal human The Rottapel lab has shown that 3BP2 has pleiotrophic function controlling bone homeostasis, immune cell
- Ep 106 with Dr. Bruno Giros
Since 2008, he has arrived at McGill University as a Canada Research Chair. At McGill, his laboratory has two main axes of research: 1) Studying interindividual vulnerability to Bruno Giros has trained 59 master's, doctoral and postdoc students, most of his trainees obtain positions Giros has published more than 200 publications with an H factor of 79 and 32,000 citations (Google Scholar ) and has received several distinctions, including the CNRS silver medal, the FRM "Young Researcher"
- Ep 07 with Dr. Paul Insel
Paul thinks broadly about science and has been actively publishing papers about his ideas on how COVID For the past 30 years, he has been the Director of MD/Ph.D. training program at UCSD and has served as
- Illuminating Functional Selectivity and Allosterism at GPCRs.
He has received many awards, including a Canada Research Chair, FRSQ scholarships and the CDA/CSEM/Merck He has developed innovative methods for in-cellulo measurement of protein-protein interactions, receptor His research program also studies the allosteric, biased signalling regulation of GPCR and has contributed He has contributed to the generation of many intellectual property agreements and patents, and published
- Ep 111 with Chloe Hicks
She has been an undergraduate student member in the Rajagopal Lab since January 2021 and has contributed activation of Atypical Chemokine Receptor 3 (ACKR3), a receptor which does not couple to G protein and has
- Biased agonism at the GLP-1 receptor: from structure to animal models of disease
Recently, his team has applied cryo-EM to elucidation of the structure and dynamics of GPCRs. Prof. Sexton has published over 335 peer reviewed journal articles and has been cited >29,000 times (Google Rand Medal (ASCEPT), Paxinos-Watson Award (Australian Neuroscience Society), Vane Medal (BPS), Gordon Hammes
- Ep 34 with Dr. Brian Arey
He then moved to work in the pharmaceutical industry where he has held positions of increasing responsibility Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular Arey’s laboratory discovered the first described synthetic agonists and antagonists of the FSHR and has
- Ep 35 with Dr. Brian Arey
He then moved to work in the pharmaceutical industry where he has held positions of increasing responsibility Brian has contributed to the discovery or development of 5 marketed drugs through his work spanning molecular Arey’s laboratory discovered the first described synthetic agonists and antagonists of the FSHR and has
- Ep 71 with Dr. Jean Martin Beaulieu
Beaulieu has pioneered work establishing a role for Beta-arrestin signaling in the brain in vivo and has established its importance in D2 dopamine receptors (D2R) functions. Work by the Beaulieu Lab has demonstrated that mood stabilizer drugs (e.g. lithium) used for bipolar Working in collaboration with geneticists, the Beaulieu-Lab has identified interactions between cellular These investigations have led to the identification of an RNA binding protein (FXR1P) involved in the
- Ep 56 with Dr. Adriano Marchese
Adriano’s research has contributed to our understanding of the role that ubiquitin plays in GPCR signaling His lab has shown a role for -arrestins and PTMs in GPCR trafficking and signaling and has leveraged
- Interrogating Multiscale Receptors Functions in Space
Beaulieu has pioneered work establishing a role for Beta-arrestin signaling in the brain in vivo and has established its importance in D2 dopamine receptors (D2R) functions. Work by the Beaulieu Lab has demonstrated that mood stabilizer drugs (e.g. lithium) used for bipolar Working in collaboration with geneticists, the Beaulieu-Lab has identified interactions between cellular These investigations have led to the identification of an RNA binding protein (FXR1P) involved in the
- Ep 08 with Dr. Graciela Pineyro
She has done extensive work on the molecular pharmacology of opioid receptors and is currently focusing We chatted about how the current pandemic has affected her personally and professionally. Dr.
- Ep 114 with Dr. Robert F. Bruns
., he retired at the end of 2014 and since then has been writing papers on his final major project at Lilly, a dopamine D1 PAM series that has advanced through Phase 2 clinical trials. Bruns has over 80 publications and 11,000 citations, with an h-index of 47. Dr. Robert F.
- Ep 89 with Dr. Patrick Sexton
More recently, his team has been at the forefront of the application of cryo-EM to elucidate of the structure Sexton has published over 320 peer-reviewed journal articles and has been cited >26,000 times (Google Rand Medal (ASCEPT), Paxinos-Watson Award (Australian Neuroscience Society), Vane Medal (BPS), Gordon Hammes
- Ep 70 with Dr. Stephen Ferguson
He has held four Canada Research Chairs since 2001 and was previously a Heart and Stroke Foundation of He has also received both Junior (2001) and Senior (2005) investigator awards from the Pharmacological His research career has focused on the investigation of the regulation of G protein-coupled receptors
- Ep 151 with Dr GPCR Board
Trejo’s research has focused on PAR1, which has important functions in hemostasis, thrombosis, inflammation She has made numerous important discoveries related to the mechanisms that control PAR1 signaling and is the recognized expert on protease-activated receptors, particularly PAR1, and over the years she has Trejo has presented her studies at 52 national/international meetings and 66 academic seminars across GPCR About Anne Marie Quinn "Anne Marie Quinn has a long and varied work experience in the biocomputing