September 2022 Sweet taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation Autophagy deficiency in myeloid cells plays a causal role in eosinophilic CRS (ECRS) via macrophage IL autophagy‐enhancing agent, trehalose, or related sugar compounds, and the underlying mechanism focusing on macrophage IL Methods We investigated the therapeutic effects of trehalose and saccharin on macrophage IL‐1β production

Activation of Mrgpra2 by defensin triggered neutrophil release of IL-1β and CXCL2 which are vital for

phosphorylation of p38 MAPK, ERK1/2 and CREB in the late phase of arthritis was associated with increased IL

Oncology and Immunology GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL -23/IL-17 axis signal pathway Published date September 10, 2024 Abstract "Skin psoriasis is defined as receiving external stimulation to activate skin dendritic cells (DCs) which can release interleukin 23 (IL as induce T helper 17 (Th17) cell differentiation leading to elevated production of interleukin 17 (IL

and Immunology Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL treatment induced high IFN-γ, CD69, and CD25 expression, but surprisingly did not induce substantial IL IL-2 3'UTR activity. This may explain the inhibitory impact on IL-2 production in hM3Dq/β1T cells. that activating the pAKT pathway is critical for IL-2 production in T cells."

lymphoid cell , HES , High-affinity Fc receptor for IgE , Hypereosinophilic syndrome , IFNG-AS1 , IFNγ , IL , IL-13R , IL-13Rα1/2 , IL-1RαP , IL-31R , IL-31RA , IL-33R , IL-4Rα , IL-5Rα , ILC , ILC2 , IRF1 ,