September 2022 Sweet taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation Autophagy deficiency in myeloid cells plays a causal role in eosinophilic CRS (ECRS) via macrophage IL autophagy‐enhancing agent, trehalose, or related sugar compounds, and the underlying mechanism focusing on macrophage IL Methods We investigated the therapeutic effects of trehalose and saccharin on macrophage IL‐1β production

Activation of Mrgpra2 by defensin triggered neutrophil release of IL-1β and CXCL2 which are vital for

phosphorylation of p38 MAPK, ERK1/2 and CREB in the late phase of arthritis was associated with increased IL

of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL G-protein coupled receptor D (MRGPRD) in the regulation of the inflammatory mediator interleukin 6 (IL stimulating human MRGPRD-expressing HeLa cells with the agonist β-alanine, we observed a release of IL IkB kinases (IKK)-mediated canonical activation of nuclear factor kappa-B (NF-κB) and stimulation of IL This IL-6 release could be blocked by a Gαq inhibitor (YM-254890), an IKK complex inhibitor (IKK-16),

Currently, inhibitors of IL-31, IL-4/13, NK1 receptors, opioids and cannabinoids, JAK, PDE4 or TRP are

tissues from the patients. hDPSCs isolated from the healthy pulp tissues were stimulated by LPS, TNFα and IL

October 2022 "CXCR1 and CXCR2 chemokine receptors, mainly activated by interleukin 8 (IL-8 or CXCL8),

August 2022 "CXCR1 and CXCR2 chemokine receptors, mainly activated by interleukin 8 (IL-8 or CXCL8),

personalized cancer therapy GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL -23/IL-17 axis signal pathway Structural and Molecular Insights into GPCR Function Exploring the constitutive

Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production

ACE2 Activation by Tripeptide IRW (Ile-Arg-Trp) Depends on the G Protein-Coupled Receptor 30 Signaling

and Signaling Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL

GPCR CD97: Filling in some of the gaps GPCR Activation and Signaling Butyrate induces STAT3/HIF-1α/IL

GPCR Binders, Drugs, and more ACE2 Activation by Tripeptide IRW (Ile-Arg-Trp) Depends on the G Protein-Coupled