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5 items found for "ILC2"
Posts (4)
- 📰 GPCR Weekly News, July 1 to 7, 2024
Emerging GPCR targets for AUD: Insights from preclinical studies CB2 stimulation of adipose resident ILC2s
- GPCR kinases generate an APH1A phosphorylation barcode to regulate amyloid-β generation
Significantly, we show that GRKs generate distinct phosphorylation barcodes in intracellular loop 2 (ICL2 molecular dynamics simulation studies reveal an interaction between the βarr2 finger loop domain and ICL2
- Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E,
NF-α1/CPE-5-HTR1E, it recruited β-arrestin1 by forming numerous salt bridges and hydrogen bonds to ICL2
Other Pages (1)
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
< GPCR News < GPCRs in Oncology and Immunology CB2 stimulation of adipose resident ILC2s orchestrates Group 2 innate lymphoid cells (ILC2s) play a critical role in maintaining adipose homeostasis via the endocannabinoid system, is expressed on both visceral adipose tissue (VAT)-derived murine and human ILC2s Our results show that CB2 stimulation of ILC2s protects against insulin-resistance onset, ameliorates therapeutic effects of CB2 are mediated through activation of the AKT, ERK1/2, and CREB pathways on ILC2s