Emerging GPCR targets for AUD: Insights from preclinical studies CB2 stimulation of adipose resident ILC2s

Significantly, we show that GRKs generate distinct phosphorylation barcodes in intracellular loop 2 (ICL2 molecular dynamics simulation studies reveal an interaction between the βarr2 finger loop domain and ICL2

NF-α1/CPE-5-HTR1E, it recruited β-arrestin1 by forming numerous salt bridges and hydrogen bonds to ICL2

communication networks between the Nb80 and the ligand-binding sites, primarily involving residues around ICL2