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Bicarbonate signalling via G protein-coupled receptor regulates ischaemia-reperfusion injury GPCRs in

lactate receptor GPR81/HCAR1 in the brain: a putative therapeutic target for the treatment of cerebral ischemia

Immunology Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic

(IBD) is characterized by dysbiosis of the gut microbiota and dysfunction of intestinal stem cells (ISCs However, the direct interactions between IBD microbial factors and ISCs are undescribed. Here, we identify α2A-adrenergic receptor (ADRA2A) as a highly expressed GPCR in ISCs. regulation of ISCs and colitis exacerbation and yielding a targeted therapeutic approach to restore ISC function in colitis."

Contest Committee Sponsors GPCR Retreat Program < Back to schedule Dopamine-Mediated Motor Recovery after Ischemic

Immunology Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure Published date April 1, 2023 Abstract " Aims: A causal link between non-ischaemic heart Methods: Ninety-five non-ischaemic HF patients undergoing transcatheter endomyocardial biopsy and 60 required before specific therapies directed at GPCR autoantibodies can be clinically tested in non-ischaemic Tags Chronic non-ischaemic heart failure , Heart failure , Pathophysiology .