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(IBD) is characterized by dysbiosis of the gut microbiota and dysfunction of intestinal stem cells (ISCs However, the direct interactions between IBD microbial factors and ISCs are undescribed. Here, we identify α2A-adrenergic receptor (ADRA2A) as a highly expressed GPCR in ISCs. regulation of ISCs and colitis exacerbation and yielding a targeted therapeutic approach to restore ISC function in colitis."

Contest Committee Sponsors GPCR Retreat Program < Back to schedule Dopamine-Mediated Motor Recovery after Ischemic

Immunology Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure Published date April 1, 2023 Abstract " Aims: A causal link between non-ischaemic heart Methods: Ninety-five non-ischaemic HF patients undergoing transcatheter endomyocardial biopsy and 60 required before specific therapies directed at GPCR autoantibodies can be clinically tested in non-ischaemic Tags Chronic non-ischaemic heart failure , Heart failure , Pathophysiology .

Some of my data were also used in an In-vivo study published in iScience, showing the relevance of the