Scientific Data by Arne Hansen et a l has introduced a sensitive method for detecting GPCR mRNAs in human immune cells and platelets, revealing significant findings that enhance our understanding of GPCRs' roles in immune Additionally, the study identified unique expression patterns of GPCRs in different immune cell types immune responses and highlights the need for further functional studies to elucidate their specific Therefore this study significantly advances our understanding of GPCR expression in human immune cells

2022 "The endocannabinoid system plays a key role in the intersection of the nervous, endocrine, and immune It is well known that immune challenges, such as exposure to lipopolysaccharide, the main component of

interfollicular regions of lymphoid tissues through binding the EBI2 (GPR183) to stimulate effective adaptive immunity

< GPCR News < GPCRs in Oncology and Immunology Chemoattractant receptor signaling in humoral immunity Published date April 4, 2024 Abstract "Efficient induction of humoral immune responses depends on orchestrated chemoattractant receptors and plays an important role in the control of B cell migration during humoral immune summarize the current understanding of chemoattractant receptor signaling in the context of humoral immunity Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology

as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases Published date Herein we propose a model for immune conditioning, whereby metabolites such as butyrate affect immune Deficiency of SCFA would lead to pro-inflammatory immune cell skewing through insufficient G-protein Such pro-inflammatory immune cells may travel to tissues such as the brain, the lung, the kidney etc Western lifestyle diseases, most of which are immune based, in tissues remote from the gut."

kinases in immune cells identify pleiotropic and cell type-specific functions Published date November Immune cells commonly express two to four members of the GRK family (GRK2, GRK3, GRK5, GRK6) simultaneously , but we have very limited knowledge about their interplay in primary immune cells. Together, our findings demonstrate the complexity of GRK functions in immune cells, which go beyond GPCR Furthermore, they highlight the need for studying GRK functions in primary immune cells to address their