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18 items found for "Incidence trends"
- 📰 GPCR Weekly News, July 10 to 16, 2023
Colorectal cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004-2018.
- 📰 GPCR Weekly News, June 26 to July 2, 2023
Esophageal and gastric cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004
- 📢 GPCR Update: August 19-25, 2024 | Thrilling Announcement: New Pharmacology Course Dates & Exclusive Discounts Inside!
Dear GPCR Enthusiasts , Get ready for an exciting learning experience with our newly updated Principles of Pharmacology I & II  courses! We've refreshed the schedule and can’t wait for you to join us on these new dates. New Course Dates: Principles of Pharmacology I :  October 3, 10, 17, 24 (four sessions) Principles of Pharmacology II :  October 31, November 7, 14, 21, December 5 (five sessions) Courses Highlights Act Fast: Don’t miss this incredible opportunity to immerse yourself in the Principles of Pharmacology I & II BUNDLE . Grab this chance to deepen your understanding of pharmacology and take your knowledge to the next level! Secure your spot today and elevate your expertise! Premium members enjoy a 5-day free trial—join now and save with the 25% OFF early bird discount . Enrollment is now open to the public! Topics include pharmacologic activity measurement, mechanisms of action, and GPCR discovery strategies. Take advantage of a 25% early bird discount for premium members! Topics cover new cellular assays, real-time kinetics, and unique GPCR behaviors. Secure your spot now by signing up today! Did you know...? As a premium member , you can access over 500 minutes of exclusive, expert-led content from esteemed leaders, Drs. Kenakin and Hoare . We highly recommend exploring valuable resources such as ' Applying Pharmacology to Drug Discovery ' and ' Advanced Data Analysis for GPCR Pharmacology' ." GPCR Event Spotlight   11th Adhesion GPCR Workshop   Location:  Mexico City Dates:  October 23-25, 2024 Connect with peers and delve into cutting-edge adhesion GPCR biology. Interested in boosting your brand? Reach out to us at Hello@DrGPCR.com for sponsorship opportunities .  Let’s dive into the  Classified GPCR News  from August 19th to 25th, 2024 GPCR Activation and Signaling Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling GPCR Binders, Drugs, and more Selenomethionine Promotes Milk Protein and Fat Synthesis and Proliferation of Mammary Epithelial Cells through the GPR37-mTOR-S6K1 Signaling GPCRs in Neuroscience Astrocyte Gi-GPCR signaling corrects compulsive-like grooming and anxiety-related behaviors in Sapap3 knockout mice Methods & Updates in GPCR Research Genome-wide identification of 769 G protein-coupled receptor (GPCR) genes from the marine medaka Oryzias melastigma Industry News Cumulus Oncology and leadXpro Achieve Critical Milestone in GPR68 Drug Discovery Project Ambrosia lands $16m to ‘improve on existing GLP-1 drugs’ Opening Ceremony of Xuzhou Zhongshu Research Site and CNS Drug Innovation Forum Nxera Pharma Notes Positive Phase 2 Data for Partnered Schizophrenia Candidate NBI-1117568 Call for GPCR Papers NEW Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and Webinars September 5 - 6, 2024 | 4th Transatlantic ECI GPCR Symposium September 18, 2024 | FREE Webinar - The value of GPCR cell-based assays in drug discovery NEW September 30 - October 3, 2024 | 22nd Discovery on Target October 2024 | Biologics US 2024  October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry October 17, 2024 | Unprecedented fragment-based screening using Spectral Shift for GPCRs October 23 - 25, 2024 | 11th Adhesion GPCR Workshop November 5 - 7, 2024 | 16th Annual PEGS Europe  July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs NEW Research Associate Postdoc in GPCR mechanosensing  Postdoctoral Position Postdoctoral research position Senior or Lead Researcher  Become a Premium Member! Get your 5-day free trial TODAY!
- Focusing on the role of secretin/adhesion (Class B) G protein-coupled receptors in placental...
Preeclampsia, a clinical syndrome mainly characterized by hypertension and proteinuria, with a worldwide incidence
- 📰 GPCR Weekly News, April 8 to 14, 2024
Let’s dive into the Classified GPCR News from April 8th to 14th, 2024 Adhesion GPCRs High incidence of
- Integration and Spatial Organization of Signaling by G Protein-Coupled Receptor Homo- and ...
receptors are responsible for signal recognition at the membrane level and information transduction inside
- Disentangling bias between G q, GRK2, and arrestin3 recruitment to the M 3 muscarinic acetylcholine
G protein-coupled receptors (GPCRs) transmit extracellular signals to the inside by activation of intracellular
- Fly casting with ligand sliding and orientational selection supporting complex formation of a GPCR..
During this sliding, bosentan passes the gate of the binding pocket from outside to inside of the pocket
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
This whitepaper will provide an overview of G Protein-Coupled Receptors (GPCRs) and discuss current trends have an enhanced capacity to elicit receptor internalization, thereby gaining the capacity to shelter inside receptor internalization in a process that pulls the ligand, together with its conjugated payload, inside
- 📰 GPCR Weekly News, October 23 to 29, 2023
Get the inside scoop by subscribing to our monthly Dr.
- 📰 GPCR Weekly News, February 13 to 19, 2023
From outside to inside and back again: the lysophosphatidic acid-CCN axis in signal transduction.
- GRK2 in cardiovascular disease and its potential as a therapeutic target
in the field of heart failure (HF) research, case numbers and overall mortality remain high and have trended
- High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...
At a median follow-up interval of 67.1 months, a significant trend towards reduced distant metastasis-free
- 📰 GPCR Weekly News, September 18 to 24, 2023
Cryo-EM structures of human GPR34 enable the identification of selective antagonists Industry News Inside
- 📰 GPCR Weekly News, August 28 to September 3, 2023
the pathophysiology and treatment of CNS disorders GPCRs in Oncology and Immunology From outside to inside
- 📰 GPCR Weekly News, November 6 to November 12, 2023
abplex method for high-throughput gpcrs antibody discovery Reviews, GPCRs, and more Current strategic trends
- Glyco-sulfo hotspots in the chemokine receptor system
key role in CCL3 and CCL5 binding (Bannert N et al. 2001) as well as to exist in heterogeneous forms inside
- Structural landscape of the Chemokine Receptor system
The 30s-loop of chemokines can bind either on top of the extracellular loop 2 (ECL2) or inside the major