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793 items found for "Interleukin-13 receptor alpha 1/2"
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- Dr. GPCR Ecosystem 2.0
Welcome to the new and improved Dr. GPCR Ecosystem. In this mini video course, I want to walk you through our new website and show you what the ecosystem has to offer to its members.
Posts (542)
- Anosmin 1 N-terminal domains modulate prokineticin receptor 2 activation by prokineticin 2
Prokineticins (PKs) exert their biological functions through the activation of the G protein-coupled receptors (GPCRs) prokineticin receptor 1 and 2 (PKR1, 2), and mutations in the PK2 and PKR2 genes are involved this protein is able to enhance the activation of the ERK1/2 (extracellular signal-regulated kinase 1 /2) pathway elicited by PK2 through PKR2. the binding to PKR2 and in the modulation of the activation of the receptor by PK2.
- Biased Agonism at the GLP-1 Receptor: A Pathway to Improved Therapeutic Outcomes
(GPCRs) like the glucagon-like peptide-1 receptor (GLP-1R). diabetes and obesity [2]. Nat Rev Drug Discov, 2013. 12 (3): p. 205-16. 2. ., Profiling Glucagon-Like Peptide -1 Receptor Transducer Coupling, Signalling and Biased Agonism . 2023 ., Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist.
- Function and structure of bradykinin receptor 2 for drug discovery
October 2022 "Type 2 bradykinin receptor (B2R) is an essential G protein-coupled receptor (GPCR) that
Other Pages (248)
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
, Interferon-gamma , Interleukin , Interleukin-1 receptor alpha P , Interleukin-13 receptor , Interleukin -13 receptor alpha 1/2 , Interleukin-31 receptor , Interleukin-31 receptor A , Interleukin-33 receptor , Interleukin-4 receptor alpha , Interleukin-5 receptor alpha , JAK , JAK inhibitors , JAKi , Janus subunit beta , PAR2 , PC(20) , PN , Protease activated receptor 2 , Provocative concentration causing , Transient receptor potential , Transient receptor potential ankyrin 1 , Transient receptor potential
- The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor
< GPCR News < GPCRs in Oncology and Immunology The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor Published date April 29, 2024 Abstract "G protein-coupled receptors (GPCRs) regulate many cellular processes in response to various stimuli, including light, mice immunized with myelin oligodendrocyte glycoprotein 35-55 produced high amounts of interferon-γ, interleukin -17A, and interleukin-6 compared with those from wild-type mice.
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
cells Published date June 12, 2023 Abstract "T cell antigen receptor stimulation induces tyrosine phosphorylation to activate the phosphatidylinositol pathway and induce interleukin-2 production in Jurkat leukemic Importantly, costimulation of both muscarinic receptors plus the TCR even led to reduced IL-2 expression AP-1. IL-2 3'UTR activity.