Jürgen Wess and Liu Liu for their study on A novel function of the M2 muscarinic receptor Drs.

GPCR Summit 2022 is less than a month away!

February 2022 "Switzerland Today, InterAx Biotech is pleased to announce that Carola Weiss has joined Carola Weiss is a Senior Executive with more than 20 years of international experience in the biopharmaceutical Carola Weiss ’ professional career brings deep expertise in business development, marketing & sales,

The move comes less than three weeks after X4 pulled together a $55 million PIPE and amended a loan facility

., Wess, J., & Kobilka, B. K. (2013).

We will first summarize their prominent roles in GPCR pharmacology before transitioning into less well-explored

In a constant effort to develop drugs with less side effects, and tools to explore the ORs nature and

Here, we will focus on the relatively less well-studied effects of GPCRs in cardiac fibroblasts, focusing

In less than a decade, nanobodies, or recombinant single-domain antibody fragments from camelids, have

November 2021 "Target class-specific libraries mean you need to screen less to identify high-quality

In contrast, less is known about the expression and function of the GLP-1R in human T cells.

Although less characterized, canonical CKRs have also been shown to not only directly regulate migration

dynamics of GPCR activation has always been a challenge because G protein activation in cells occurs in less

Reviews, GPCRs, and more Diversification processes of teleost intron-less opsin genes.

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exhibit varying degrees of negative intrinsic efficacy, leading to the presence of both robust and less

ligands that bind directly to the receptor's active site, allosteric modulators target distinct, often less

Although less characterized, canonical chemokine receptor systems have been also shown to not only directly

This Week’s Highlights: Celebrating Excellence: Wessel A. C.

GPCRs are valuable drug targets linked to serious diseases, many remain undrugged because they are less While the native ligand conjugate exhibited poor selectivity for CCR5-expressing cells and was less effective

Cryo-EM, on the other hand, requires less protein and has evolved to achieve resolutions comparable to