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981 items found for "Jespers W"

Programs (3)

  • Applying Pharmacology to Drug Discovery

    To join our waitlist please fill out this form - https://forms.gle/xPZjX56LkEvhGv6b6 We'll let you This allows predictions of drug activity in all physiological systems, not only the system where testing What makes each drug type unique to therapeutic pharmacology? 3. Modules: Week 1 - Fundamentals of Pharmacology Week 2 - Characterizing Agonists Week 3 - Characterizing Kenakin during the 4 weeks, scheduled according to the professor's availability.

  • Dr. GPCR Ecosystem 2.0

    Welcome to the new and improved Dr. GPCR Ecosystem. In this mini video course, I want to walk you through our new website and show you what the ecosystem

  • Advanced data analysis for GPCR pharmacology

    - Understanding the pharmacology data analysis framework we use for GPCRs. ability to perform, understand, and communicate GPCR pharmacology data analysis to a high level, as well Attendees will be provided with Prism files, Excel templates and simulators, and the PowerPoints of the workshop Hoare during or after the four weeks, scheduled according to the professor's availability. Participants who complete the course will get an online certification signed by the professor and the

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Posts (541)

  • Exciting GPCR Events for Next Year! + GPCR Weekly Rocket Launch ⦿ Oct 28 - Nov 3, 2024

    🚀✨ This Week’s Highlights: Congrats to: Ya-Tzu Li , our notable contributor, for her superb undergrad about State transitions of coupled Gi-protein: Insights into internal water channel dynamics within dopamine would you want to miss out on all the fun with a DrGPCR Premium Membership ? Discounted GPCR courses - because who doesn't love a good deal?  Drugs like Ozempic will change the world GPCR Events, Meetings, and Webinars November 5 - 7, 2024 | 16th

  • 📰 GPCR Weekly News, March 25 to March 31, 2024

    Check out our GPCR coverage for this week. We have 17 GPCR papers and eight industry news. This week's highlight includes congrats to: Junyi Liang, Niña Caculitan, and Adam W Smith for their research GPCR University hands-on workshop with Dr.  Hoare's workshop for individuals who live and work in developing countries. If you have a few minutes to spare and have participated in our symposiums, we would appreciate it if

  • Design and validation of recombinant protein standards for quantitative Western blot analysis of...

    October 2022 Design and validation of recombinant protein standards for quantitative Western blot analysis Results: Here we generated highly soluble and stable recombinant protein constructs GST-CB1414-472 and CB1 receptor C-terminal tail for use as standard and negative control, respectively, in quantitative Western To this end we used three different antibodies, all raised against a peptide comprising the C-terminal Estimated values of CB1 receptor density obtained by quantitative Western blot were of the same order

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Other Pages (437)

  • Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors

    Here we used a dataset of mutations found in patient samples derived from the Genomic Data Commons and We explored cancer-related mutation patterns in all GPCR classes combined and individually. Authors Bongers B J , Gorostiola González M , Wang X , van Vlijmen HWT , Jespers W , Gutiérrez-de-Terán H , Ye K , IJzerman AP , Heitman LH , van Westen GJP. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • The Effect of Cancer-Associated Mutations on Ligand Binding and Receptor Function - A Case for the 5-HT2C Receptor

    In this study, we aimed to investigate the effects of cancer patient-derived 5-HT2C receptor mutations We found that the affinity of the endogenous agonist serotonin (5-HT) and inverse agonist mesulergine were both drastically decreased by mutations L209HECL2 and F328S6.52, which are located in the orthosteric Authors Chenlin Feng, Rongfang Liu, Reno Brooks, Xuesong Wang, Willem Jespers, Marina Gorostiola González GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Attendees Authors & Affiliations "Rosell, Júlia (1) Holmkvist, Jesper L. (1) Arastoo, Mohammad Reza Smith (Harvard Medical School, Brigham and Women's Hospital); Meredith A. I work under the supervision of Dr. Peng Xiao on the web ResearchGate < Previous Session Next Session >

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