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53 items found for "Ji'ou Gu"
- GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy in Colorectal Cancer
progression of CRC. " Authors Junwei Tang , Wen Peng , Jiangzhou Ji , Chaofan Peng , Tuo Wang , Peng Yang , Ji'ou Gu , Yifei Feng , Kangpeng Jin , Xiaowei Wang , Yueming Sun Tags GPCR , autophagy , growth , homology
- G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells
estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate their C-terminal tails through which they interact in the plasma membrane with membrane-associated guanylate
- GPR56: GPCR as a guardian against ferroptosis
< GPCR News < GPCRs in Oncology and Immunology GPR56: GPCR as a guardian against ferroptosis Published
- Content Guidelines | Dr. GPCR Ecosystem
Content Guidelines FindYooour, LLC (“FindYooour”) provides its Service to you through our websites referred General Guidelines Ecosystem.DrGPCR.com allows users to contribute different kinds of content, including Playing nice isn't rocket science, but just in case, we've put together these general guidelines. Please also read the guidelines below for specific types of content that you might contribute to the Review Guidelines The best reviews are passionate and personal.
- Be Our Guest | Dr. GPCR Ecosystem
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- Advanced data analysis for GPCR pharmacology | Dr. GPCR Ecosystem
He regularly teaches courses and publishes chapters and guides on basic and advanced pharmacology and Sam is an editor at the NIH Assay Guidance Manual. worked as a pharmacology leader in the pharmaceutical industry for 15 years at Neurocrine Biosciences, guiding
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Jin-Peng Sun’s Lab since I graduated from Shandong University in 2012, and worked under the guidance
- Ep 37 with Dr. Samuel Hoare
He guided the in vitro biology efforts of the company for numerous drug discovery campaigns.
- Ep 88 with Dr. Hannes Schihada
fellowship to Stockholm, Sweden, in order to focus my research on class Frizzled GPCR s in the lab of Gunnar
- Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
This effect is reduced by pertussis toxin (PTX) and GUE1654, a biased antagonist for the Gβγ pathway small GTPases in the formation of actin-rich projecting structures, we identified the PI3K-regulated guanine
- Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer
signaling that go beyond targeting GPCRs. " Authors Jingyi Zhao , Vincent DiGiacomo , Mariola Ferreras-Gutierrez
- Ep 120 with Brendan Wilkins
molecular pharmacology of GPR146 and to validate the proposed ligands of GPR146 in line with IUPHAR-NC guidelines
- The landscape of cancer-rewired GPCR signaling axes
Clubb, Lorenzo Amir Nemati Fard, Giorgos Kargas, Giuseppe R Diaferia, Ranka Vukotic, Luana Licata, Guanming Wu, Gioacchino Natoli, J Silvio Gutkind , Francesco Raimondi Tags GPCR , cancer , cancer cell lines
- Newsletter for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Up Abstract Submission Submit your research abstracts following our guidelines to present at the conference
- A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages
Indeed, gut microbiota dysbiosis and metabolomic profile alterations, are hallmarks of IBD.
- The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells and boosts HIV-1 R5 replication
Authors Adeline Guigues , Sandrine Gimenez , Clément Mettling , Damien Maurel , Etienne Doumazane , Laurent
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
Authors Amos Hong Pheng Loh , Min Thura , Abhishek Gupta , Sheng Hui Tan , Kelvin Kam Yew Kuan , Koon
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
Authors James Sinnett-Smith, Tarique Anwar, Elaine F Reed, Yaroslav Teper, Guido Eibl, Enrique Rozengurt
- Deciphering the genetic landscape of lumpy skin disease: Unraveling variable virulence through comprehensive genome sequence analysis in India
Authors R Mishra, S K Biswas, S Nandi, S Mahajan, K G Sai Balaji, V Gairola, D Poloju, S Gulzar, K P
- Travel Tips for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
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- Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
Bernardes , Neha Mishra , Thomas Bahmer , Jeanette Franzenburg , Bimba F Hoyer , Andreas Glück , Martina Guggeis
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
the Immune System, and Western Diseases Published date November 20, 2023 Abstract "We show that the gut This model helps explain how the gut microbiome may be affecting peripheral immune cells, and consequently Western lifestyle diseases, most of which are immune based, in tissues remote from the gut." Authors Quanbo Wang , Charles R Mackay Tags Gut microbiota , Western lifestyle diseases , portal vein
- The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells
intestinal dendritic cells Published date October 29, 2024 Abstract "The intestinal lumen is rich in gut microbial metabolites that serve as signaling molecules for gut immune cells. G-protein-coupled receptors (GPCRs) sense metabolites and can act as key mediators that translate gut However, the impacts of gut microbe-GPCR interactions on human physiology have not been fully elucidated Here, we show that GPR31, which is activated by the gut bacterial metabolite pyruvate, is specifically
- Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy
Authors Yi Tang, Ye Tian, Chun-Xia Zhang, Guo-Tai Wang Tags G Protein-coupled receptors , Olfactory receptors
- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
prior to enrollment with (n = 72) or without (n = 58) Long-COVID diagnosis according to the German S1 guideline
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
Whereas it is well established that single-cell migration is often guided by gradients of chemokines By combining experimental data with theory on leukocyte chemotaxis guided by the G protein-coupled receptor We further show that these self-generated gradients can sustain the long-range guidance of DCs, adapt collective migration patterns to the size and geometry of the environment, and provide a guidance cue
- A2aR on lung adenocarcinoma cells: A novel target for cancer therapy via recruiting and regulating tumor-associated macrophages
Authors Ying Bai , Xin Zhang , Jiawei Zhou , Jianqiang Guo , Yafeng Liu , Chao Liang , Wenyang Wang ,
- Ep 145 with Dr John Janetzko
John expressed his comfort in sharing his stories and agreed to follow Yamina's guidelines. adequately prepare postdocs for the transition to industry or academia, suggesting a detailed manual or guide