Previous studies have identified the pivotal role of Lysophosphatidic acid (LPA)-signaling in ovarian Authors Ji Hee Ha , Rangasudhagar Radhakrishnan , Revathy Nadhan , Rohini Gomathinayagam , Muralidharan

By The GAIN Domain Tobias Langenhan Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong In addition, a significant role of GPR110 in blood brain barrier (BBB) function has been discovered. Recently, evidence for sex has been described in choanoflagellates, the closest living relatives of animals Importantly, the signaling pathways underlying sexual reproduction in these different contexts have not I have a particular interest in understanding the premetazoan function of adhesion GPCRs."

These results highlight the potential RGS2 inhibitors have to be a new class of chemotherapeutic agents Authors Adam Bair, Natalie Printy, So Hee Choi, Joshua Wilkinson, Joseph O'Brien, Brian Myers, David

neutrophil chemotaxis. " Authors Xuehua Xu , Xi Wen , Smit Bhimani , Amer Moosa , Dustin Parsons , HyunGee Ha , Tian Ji .

Ethanol consumption has been associated with exacerbation of neurodegenerative and systemic inflammatory Authors Sharmistha Banerjee , Taeyeop Park , Yoo Sun Kim , Hee-Yong Kim Tags Adenylyl cyclase , Cytokines

Authors Sun-Hee Hwang , Kevin Andrew White , Bandarigoda Nipunika Somatilaka , Baolin Wang , Saikat Mukhopadhyay

thereby promoting the tumorigenesis and progression of CRC. " Authors Junwei Tang , Wen Peng , Jiangzhou Ji

protein-coupled receptor (GPCR) that is implicated in different physiological pathways in the brain, and has Conclusion: GPR37 had diagnostic and prognostic value in glioma. Zou , Yuhao Weng , Chengxiang Peng , Zhichao Xu , Jingbai Zhang , Xiaorui Liu , Xiao Pang , Yunxiang Ji

Torrelli-Diljohn · Emmanouil Kyrloglou · Vasiliki Karagiannakou · Lara-Sophie Brodmerkel · Rashed Rezwan Parag · Hailey 00 AM Session VI AGPCRs shaping the nervous system Yimin Zou · Dimitris Placantonakis · Nicole Perry-Hauser Determinants Of GAIN Domain Autoproteolysis And Cleavage Resistance Of Adhesion G Protein-Coupled Receptors Hailey Júlia Rosell Tethered Agonist Dependent ADGRL3 Signaling Activity In The G12/13 Pathway Nicole Perry-Hauser Interacts With The Notch Pathway To Control Germ Cell Proliferation Ana Lilia Moreno Salinas Characterizing hADGRE5

Authors Junyi Liang , Mohamed Seghiri , Pradeep Kumar Singh , Hyeon Gyu Seo , Ji Yeong Lee , Yoonjung

Wang , Lu Wang , Yang Yang , Min Ren , Yanlin Li , Zixu Gao , Shaoluan Zheng , Yiteng Ding , Jiani Ji

The role of GPR56 in the kidneys has been understudied. Authors & Affiliations "Hailey Steichen, Krystin Eaton, Teagan Yan, and Nathan Zaidman; Department of conserved GAIN domain, that directly precedes 7TM, adopts a parallel orientation to the membrane and has Nevertheless, the role of GPR110 signaling in behavioral consequences has not been fully explored. consequences associated with the GPR110 receptor. " Authors & Affiliations "Joel Toro, Bill Huang, Hee-Yong

Randy Hall About Dr. Over the past two decades, his lab has published numerous groundbreaking findings shedding light on the Most recently, his lab has made a number of seminal contributions to understanding the signaling, regulation Randy’s lab has a special interest in studying disease-associated mutations to human GPCRs that perturb Randy has received a number of research prizes, including the PhRMA New Investigator Award, the Distinguished

Oliver Hartley About Dr. Oliver Hartley Oliver Hartley is VP for Drug Discovery at Orion Biotechnology . Since then Oliver has worked at the University of Geneva, where his research on peptide engineering and GPCR pharmacology has led to a series of high-profile publications and new intellectual property, and Oliver Hartley on the web LinkedIn Orion Biotechnology Dr.

About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule "Have coupled receptors and receptor activity modifying proteins in vascular biology, the Caron laboratory has Caron has received numerous awards including a Burroughs Wellcome Fund Career Award in the Biomedical

Debbie Hay About this episode Dr. Debbie Hay is presently a professor at the Department of Pharmacology and Toxicology at the University She has gained experience from working in academia and at GSK as an industrial trainee. Debbie Hay on the web LinkedIn Wikipedia University of Otago University of Auckland Google Scholar Pubmed

Hauser About Dr. Alexander S. Hauser Alexander is currently a postdoc as a member of the personalized medicine cluster in Copenhagen Alexander has a big interest in the integration of large biomedical data in genomics, structural biology Alexander had a research sabbatical with Madan Babu at the MRC Laboratory of Molecular Biology in Cambridge Hauser on the web Twitter ResearchGate University of Copenhagen LinkedIn Google Scholar Dr.

Aylin Hanyaloglu About Dr. Aylin Hanyaloglu Dr. Aylin Hanyaloglu has been a Principal Investigator at Imperial College London since 2007. Hanyaloglu undertook her postdoctoral training at the University of California, San Francisco with Professor Aylin Hanyaloglu on the web LinkedIn Researchgate Twitter Imperial College London Elsevier Loop Dr.

Catalina Ribas, is currently an Associate Professor at the University Autonomous of Madrid (UAM) and she has Molecular “Severo Ochoa” (UAM/CSIC) and belongs also to the Health Research Institute La Princesa, has During this period and her doctoral thesis, she has deepened the regulatory mechanisms of GPCR signaling In her postdoctoral period, she has participated in the identification and characterization of proteins Ribas' group has described a new interaction region in a cellular protein that has turned out to be very

His Ph.D. work has been focused on understanding the structure and activation of Class D fungal GPCRs He has developed novel tools and methodologies to study fungal GPCRs which allowed the determination This work has led to two first-authored manuscripts published in the journal Nature. Vaithish has been recognized with the MRC LMB's Max Perutz Prize for outstanding Ph.D. work and has been

podcast list Murat Tunaboylu & Ben Holland About Murat Tunaboylu "Murat Tunaboylu, Antiverse's CEO, has Mid-career, he has worked in finance and developed high-frequency trading systems. After switching to biotech, Murat has built cell imaging software and lab robots to accelerate cancer He has co-founded consultancy and biotech companies Svarlight and Antiverse. He then returned to information engineering and has been working in machine learning for nearly 10 years

Trejo’s research has focused on PAR1, which has important functions in hemostasis, thrombosis, inflammation She has made numerous important discoveries related to the mechanisms that control PAR1 signaling and Trejo has been continuously funded by the NIH for >20 years and was a recipient of the prestigious American is the recognized expert on protease-activated receptors, particularly PAR1, and over the years she has Trejo has presented her studies at 52 national/international meetings and 66 academic seminars across

., based in South Korea, has recently been named President of GPCR Therapeutics, USA, a newly incorporated She was a participant in numerous due diligence (anti-CXCL8 mAb) and has managed external collaborations the type I interferon-alpha receptor project, licensed to AstraZeneca (Saphnelo™ Anifrolumab) that has She has extensive experience working with Biologics, and Antibody Drug Conjugates as well as experience She has also authored forty-six peer-reviewed publications. Dr.

He has focussed on developing a comprehensive map of ovarian cancer essential genes using whole genome This approach has provided insight into novel drivers resulting from the widespread gene copy number A second area of interest has been the elucidation of the molecular basis for a rare autosomal human The Rottapel lab has shown that 3BP2 has pleiotrophic function controlling bone homeostasis, immune cell

Since 2008, he has arrived at McGill University as a Canada Research Chair. At McGill, his laboratory has two main axes of research: 1) Studying interindividual vulnerability to Bruno Giros has trained 59 master's, doctoral and postdoc students, most of his trainees obtain positions Giros has published more than 200 publications with an H factor of 79 and 32,000 citations (Google Scholar ) and has received several distinctions, including the CNRS silver medal, the FRM "Young Researcher"

Paul thinks broadly about science and has been actively publishing papers about his ideas on how COVID For the past 30 years, he has been the Director of MD/Ph.D. training program at UCSD and has served as

He has received many awards, including a Canada Research Chair, FRSQ scholarships and the CDA/CSEM/Merck He has developed innovative methods for in-cellulo measurement of protein-protein interactions, receptor His research program also studies the allosteric, biased signalling regulation of GPCR and has contributed He has contributed to the generation of many intellectual property agreements and patents, and published

She has been an undergraduate student member in the Rajagopal Lab since January 2021 and has contributed activation of Atypical Chemokine Receptor 3 (ACKR3), a receptor which does not couple to G protein and has