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Authors Juan Song , Miao Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin

inhibitor, suppresses the TGF-α-induced migration of hepatocellular carcinoma cells via inhibition of the c-Jun cells through the activation of AKT, p38 mitogen-activated protein kinase (MAPK), Rho-kinase and c-Jun

Authors Xin Miao , Gilbert Koch , Shichen Shen , Xue Wang , Jun Li , Xiaomeng Shen , Jun Qu , Robert

Authors Zhenyu Yao, Jun Meng, Jing Long, Long Li, Weicong Qiu, Cairong Li, Jian V Zhang, Pei-Gen Ren

demonstrate its ability to promote cancer cell motility. " Authors Yu Jin Lee , Kyeong Jin Shin , Hyun-Jun

As part of the degree, she undertook a 1-year research-based placement at the Charles Perkins Centre From here, she returned to the UK. Alastair Brown (Sosei Heptares), where she is currently a final year Ph.D. student. In particular, she is looking at L- and D-lactate-activated HCAR1 signaling. Outside the lab, she enjoys baking and swimming and has recently taken up paddle boarding.

Previously, she held the position of Vice President of Cell Biology & Pharmacology, at Bristol-Myers She was an integral contributor to two therapeutics that are FDA approved, Yervoy and Opdivo. Prior to this, she held the position of Vice President, at Medarex, Inc . She oversaw early discovery programs IL-23 p19 and IL23 p19/IL-17 bispecifics. She has also authored forty-six peer-reviewed publications. Dr.

Being a biochemist by training, she completed her Ph.D. at the Institute of Biochemistry at the University that they are huge and somehow play important roles in health and disease, fascinated her so much that she continued working on them when she started her own lab at Leipzig University. There she focused on the different modes of action of Adhesion GPCRs and found that they do not only During her medical studies in Leipzig, she had her first encounter with an orphan GPCR as the subject

She received her undergraduate degree in Biotechnology from KIIT University in India. She subsequently joined Professor Mark Connor's laboratory at Macquarie University in Australia. Sachdev pursued Ph.D. in the same lab where she investigated the molecular pharmacology of cannabinoid She is also very active within the pharmacology community and currently serves on the editorial board Given her expertise in GPCR pharmacology and scientific communication, she is poised to make valuable

She is an Associate Professor of Psychiatry at the University of Illinois at Chicago. Paul Clarck , where she studied opioid receptors. Her next career step took her to AstraZeneca as a postdoctoral trainee, where she studied animal models She then returned to academia and worked on opioids as a postdoctoral trainee with Dr. Brigitte Kieffer , where she studied ligand-directed signaling at the delta-opioid receptor.

She is also the Associate Director of the City of Hope Comprehensive Cancer Center. Dr. Vaidehi received her Ph.D. in quantum chemistry from the Indian Institute of Technology in India, where she studies on protein dynamics simulation methods at University of Southern California, and at Caltech, she She has advanced the use of computational methods to meet the challenges of designing therapeutics with She is an internationally recognized biophysicist for her contributions in developing constrained molecular

She completed her undergraduate education at Providence College, receiving a B.S. in Biology and a B.A During her time at Providence College, she received the Walsh Grant Fellowship to develop novel methods Victoria started her Ph.D. at the Tri-Institutional Ph.D. program in Chemical Biology, where she joined From there, she went on to be a research technologist in Dr. Richard Vile's lab at Mayo Clinic where she aided the evaluation of tumor-specific oncolytic viruses.

Thomas Sakmar’s laboratory at Rockefeller University, where she studies the signaling and degradation She completed her undergraduate education at Providence College, receiving a B.S. in Biology and a B.A During her time at Providence College, she received the Walsh Grant Fellowship to develop novel methods Victoria started her Ph.D. at the Tri-Institutional Ph.D. program in Chemical Biology, where she joined She is currently working to understand the signaling and degradation of GPCRs in disease states to help

Gilchrist About this episode Originally, Annette wanted to be a medical doctor but as luck has it, she didn’t get into medical school when she first applied. Instead, she discovered research and started her Ph.D. the day she should have started medical school

She obtained her Ph.D. from UFMG in 2006 and, after that, she performed her postdoctorate studies at She returned to Brazil in 2010, when she founded her independent research group. Since then, Dr. Ribeiro H factor is 28, according to Web of Science, and she is an affiliated member of the Brazilian She was able to have several grants approved in Brazil and abroad, which have granted her research group

She completed her postdoctoral fellowship at UC San Francisco under the guidance of Professor Shaun Coughlin where she worked on the newly discovered protease-activated GPCRs. Carolina in 2000 and then moved to UC San Diego School Medicine, Department of Pharmacology in 2008, where she In 2014, she was appointed Vice-Chair of the Department of Pharmacology. The long-term goal of Dr. She has made numerous important discoveries related to the mechanisms that control PAR1 signaling and

She then completed an M.Sc. in Physiology from the same university in 2005 by investigating the molecular She moved to the University of Ottawa to complete a Ph.D. in Neuroscience. She identified the molecular mechanisms involved in the opposite regulation of dopamine D1 and D5 receptors She identified the structural determinant controlling biased signaling of melatonin type 2 receptors Funded by a Wellcome Trust Seed Award, she investigated biased and compartmentalized G protein signaling

Graciela Pineyro’s love for GPCR pharmacology started in Uruguay where she first worked on the serotonin This interest in research and pharmacology took Graciela to Canada where she stayed ever since she arrived

Ilana Kotliar is a postdoctoral associate in the lab of Tom Sakmar at The Rockefeller University, where she She is a recipient of the prestigious Women in Entrepreneurship Award, an NIH T32 Training Grant, and Ilana graduated Summa cum laude from Cornell University, where she studied Chemistry and Chemical Biology

She received her undergraduate degree in biology from Truman State University and earned her Ph.D. in She then spent five years training as a postdoctoral fellow in the laboratory of Michael Caplan at Yale University, where she studied both renal physiology and sensory biology systems and focused on olfaction

She developed expertise over the past two decades studying structure/function relationships of GPCRs She received her undergraduate degree in Biotechnology from KIIT University in India. She subsequently joined Professor Mark Connor's laboratory at Macquarie University in Australia. She is also very active within the pharmacology community and currently serves on the editorial board Given her expertise in GPCR pharmacology and scientific communication, she is poised to make valuable

She has gained experience from working in academia and at GSK as an industrial trainee. Join me and learn more about Debbie’s career and what she learned through her experiences as a scientist

Katarzyna Marcinkiewicz "Katarzyna is a Senior Editor at Nature Communications, which she joined in April She obtained her Ph.D. from Weill Cornell Graduate School of Medical Sciences in New York City, studying

She oversaw an increase of the size of the Department, as well as a quintupling of its NIH funding, in The Department’s strengths lie in GPCR signal transduction and neuroscience, and she has expanded it She held faculty appointments at the University of Illinois at Chicago School of Medicine and Northwestern She has received numerous awards, including the Glaxo Cardiovascular Discovery Award, the Distinguished She gave the Fritz Lipmann Lecture at ASBMB in 2001. " Heidi Hamm on the web The Hamm Lab Vanderbilt

She pursued postdoctoral training with Nobel Laureate Dr. Oliver Smithies at UNC-CH, where she was the first to discover the essential role of adrenomedullin peptide She currently serves as Associate Editor of Physiological Reviews; the #1 ranked journal in Physiology

She earned her M.Sc. in Zoology and Neurobiology before completing a Ph.D. in Biology and Pharmacology Schwartz’s lab in Copenhagen where she completed her postdoctoral training.

She developed expertise over the past two decades studying structure/function relationships of GPCRs She completed her postdoctoral fellowship at UC San Francisco under the guidance of Professor Shaun Coughlin where she worked on the newly discovered protease-activated GPCRs. In 2014, she was appointed Vice-Chair of the Department of Pharmacology. The long-term goal of Dr. She has made numerous important discoveries related to the mechanisms that control PAR1 signaling and

Julia Gardner About Julia Gardner Julia is a senior undergraduate student at Duke University, where she She recently led a project that demonstrated the GPCR kinases (GRKs) can translocate to endosomes, and