Through PRESTO-Tango screening, we demonstrate that tyramine, primarily produced by Enterococcus via Authors Chaoliang Li , Panrui Zhang , Yadong Xie , Shishan Wang , Meng Guo , Xiaowei Wei , Kaiguang Zhang , Dan Cao , Rongbin Zhou , Sheng Wang , Xinyang Song , Shu Zhu , Wen Pan Tags Enterococcus , IBD , ISCs

He introduced molecular pharmacology to a wide range of the company's GPCR projects and was able to initiate

run in the mountains, play with Tilly (a 9-year old retired greyhound), collecting mini shoes, and hang

Hoyer , Andreas Glück , Martina Guggeis , Alexander Ossysek , Andre Küller , Derk Frank , Christoph Lange

identified physiological hormones of such under characterized ‘orphan’ receptors and functional probes for a range

Abstract " The CC chemokine receptor 6 (CCR6) is a G protein-coupled receptor (GPCR) involved in a wide range Tags CCR6 , GPCRs , Th17 cells , antibody , immune system , inflammation , therapy .

Migration of GPR4 overexpressing SK-Mel-28 cells was enhanced in a range of pH 6.5 - pH 7.5 as compared Goricnik , Julia Erl , Linda Frank , Mark Berneburg , Frank Haubner , Joachim Wegener , Stephan Schreml Tags

We further show that these self-generated gradients can sustain the long-range guidance of DCs, adapt

receptor 56 (GPR56/ADGRG1) is a multifunctional adhesion GPCR involved in diverse biological processes ranging Authors Raksha A Ganesh , Krishnan Venkataraman , Ravi Sirdeshmukh Tags GPR56 /ADGRG1 , Mesenchymal transition

Authors Ze Wu , Qiongqiong Jia , Boqun Liu , Lanlan Fang , Peter C K Leung , Jung-Chien Cheng Tags Invasion

Abstract "Phosphatase of regenerating liver 3 (PRL3) is a specific tumor antigen overexpressed in a broad range Authors Amos Hong Pheng Loh , Min Thura , Abhishek Gupta , Sheng Hui Tan , Kelvin Kam Yew Kuan , Koon Hwee Ang , Khurshid Merchant , Kenneth Tou En Chang , Hui Yi Yon , Yong Chen , Mathew Hern Wang Cheng Matthew Chau Hsien Ng , Michaela Su-Fern Seng , Prasad Iyer , Pei Ling Chia , Shui Yen Soh , Qi Zeng Tags

gut microbiota act as ligands for specific human G protein-coupled receptors (GPCRs) and modulate a range Authors Gajender Aleti , Emily A Troyer , Suzi Hong Tags G protein-coupled receptors , Gut microbiota

Authors Ahmad Raza , Meng-Chi Yen , Gangga Anuraga , Iram Shahzadi , Muhammad Waqar Mazhar , Hoang Dang Minh Xuan , Sanskriti Dey , Sachin Kumar , Adrian Wangsawijaya Santoso , Bianca Tobias William , Chih-Yang Wang Tags G-protein-coupled receptor (GPCR) , genome , glioblastoma , malignancy , molecular biomarker

Authors Hsuan Lung, Kelly L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun Kang , Sunita Ho, Edward C Hsiao Tags Wnt pathway inhibition , fibrotic bone disease , fibrous dysplasia (

of how pharmacology can greatly extend the ability to predict a candidate's therapeutic value in a range

Lange and Annie Mary Lyle Chair in Cardiovascular Research, and Professor of Pharmacology, Ophthalmology

Quick recap Yamina and Claudia had a wide-ranging discussion about Claudia's work on metabolites and

identify novel pharmacological targets and contribute to the development of innovative treatments for a range