kinin receptors, and proteases that control tumor progression, such as kallikrein-related peptidases (KLKs The expression levels of KLKs in this neoplasm are modulated by the secretome of the different cell types Considering the multiple functions of kinin receptors and KLKs, this review highlights their roles, even diagnosed in advanced stages, our efforts should focus on early diagnosis, validating for example specific KLKs Stuardo-Parada , Rodrigo López-Muñoz , Franz Villarroel-Espindola , Carlos D Figueroa , Pamela Ehrenfeld Tags KLKs