binding site of MT1 and MT2 receptors through a lateral channel between transmembrane (TM) helices IV and V. simulations which revealed different trajectories passing through the gap between TM helices IV and V Taken together, our simulations are consistent with the possibility that the gap between TM IV and V

V., & Gurevich, V. V. 2006).

β-Arrestin recruitment takes place allowing receptor internalization through clathrin-mediated pits (V. V. Gurevich, et al. 2018; Y. A. Berchiche et al. 2011).

Vesicle-associated membrane protein 2 is a cargo-selective v-SNARE for a subset of GPCRs.

Volmat, V., & Pouysségur, J. (2001). Spatiotemporal regulation of the p42/p44 MAPK pathway.

structural-and-molecular-insights-into-gpcr-function/vesicle-associated-membrane-protein-2-is-a-cargo-selective-v-snare-for-a-subset-of-gpcrs

Katharina Grotsch, Bryan L Roth, Valery V Fokin  et al. for their research on Virtual Screening of a

., Pessino, V., Mika, D., Huang, B., Wedegaertner, P. B., Conti, M., & von Zastrow, M. (2017).