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35 items found for "Krystal R Capers"
- DANGER Signals Activate G-Protein Receptor Kinases Suppressing Neutrophil Function and Predisposing to Infection After Tissue Trauma
Jinbong Park , David Gallo , Sidharth Shankar , Barbora Konecna , Yohan Han , Valerie Banner-Goodspeed , Krystal R Capers , Seong-Gyu Ko , Leo E Otterbein , Kiyoshi Itagaki , Carl J Hauser. Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Ep 96 with R. Scott Struthers
GPCR Podcast << Back to podcast list Scott Struthers R. R. Scott Struthers on the web LinkedIn Google Scholar Crinetics Radionetics Dr.
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
R) AML. The current study aimed to identify molecular predictors of response to ONV + DAC in R/R AML patients A total of 44 R/R AML patients were treated with ONV + DAC and considered evaluable for efficacy. PLK1 inhibition with ONV in combination with DAC could be a potential therapy in R/R AML patients, particularly Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis
bifunctional GLI transcription factors generate both GLI-activators (GLI-A) and GLI-repressors (GLI-R) The formation of GLI-A/GLI-R requires cilia. , and the ankyrin repeat protein ANKMY2 that direct cAMP/protein kinase-A signaling by cilia in GLI-R GLI-A formation only, or dual regulation of either lack of GLI-R or excess GLI-A formation. Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
in Axons Joseph Duman Bai1 Is A Novel Neuronal Substrate Of The Psychiatric Risk Kinase TNIK Simeon R. Kimberley Tolias Lab Bai1 Is A Novel Neuronal Substrate Of The Psychiatric Risk Kinase TNIK Simeon R. Mihaylov Abstract Only available for AGPCR 24 Attendees Authors & Affiliations "Flynn, Helen R.2, Sampedro-Castaneda Institute, UK 2Proteomics Science Technology Platform, The Francis Crick Institute, UK" About Simeon R. have recently also developed a strong interest in adhesion GPCRs and in particular, Bai1. " Simeon R.
- Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure
= -0.362, P < 0.05) and global longitudinal strain (r = -0.323, P < 0.05). myocardial mitochondrial coupling as measured by high-resolution respirometry in myocardial biopsies (r In insulin-resistant HF patients, AT2R autoantibodies were decreased (r = -.240, P < 0.05), and AT1R autoantibodies were increased (r = 0.212, P < 0.05). Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Ep 104 with Dr. Raul Gainetdinov
Raul Gainetdinov Raul R. Before SPBU, Raul R. His papers were cited over 28,000 times (H-index – 81, ISI Web of Science). In 2018-2020, Raul R.
- LP2, a cyclic angiotensin-(1-7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice
Prior to efficacy studies, immunohistochemistry on an untreated tissue array demonstrated that the AT 2 R Kinome analyses and validation of elected kinase inhibition indicated that LP2-mediated AT 2 R stimulation inhibitory potential of colorectal cancer. " Authors P Namsolleck , L de Vries , G N Moll Tags AT(2)R Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Deciphering the genetic landscape of lumpy skin disease: Unraveling variable virulence through comprehensive genome sequence analysis in India
Authors R Mishra, S K Biswas, S Nandi, S Mahajan, K G Sai Balaji, V Gairola, D Poloju, S Gulzar, K P Singh, R K Singh, G K Sharma Tags Genome sequence , Lumpy skin disease , Molecular diversity , Virulence Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
ARB1 and ARB2 correlated negatively CERAD Trail Marking A and B (R ≤ -0.26, p ≤ 0.043), while CHRM3 correlated positively with Chadler Fatigue Scale (R = 0.37, p = 0.0087). Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Ep 57 with Dr. Peter Robert Banks
These roles included management of PerkinElmer’s BioPharma R&D program and Chair of the company’s Scientific
- Ep 58 with Dr. Juan José Fung
discovery company focused on targeting GPCR heteromers in cancer, headquartered in Seoul, Korea, with an R&
- Ep 17 with Dr. Yamina Berchiche
Yamina Berchiche on the web D r.
- Ep 136 with Murat Tunaboylu & Ben Holland
Following this, he joined an early-stage medical device start-up and in 5 years was responsible for project R&
- Ep 84 with Rosie Dawaliby
I have 10 years of experience in the development and management of R&D projects and teams in the field
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
Authors Quanbo Wang , Charles R Mackay Tags Gut microbiota , Western lifestyle diseases , portal vein Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Intermediate-state-trapped mutants pinpoint G protein-coupled receptor conformational allostery
distributions among five states that lie along the activation pathway of adenosine A 2A receptor (A 2A R) Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Ep 95 with Chris Langmead
He also directs a collaborative neuroscience R&D program with Servier (France) and is the co-founder
- The landscape of cancer-rewired GPCR signaling axes
De Oliveira Rosa, Francesco Carli, Lauren Clubb, Lorenzo Amir Nemati Fard, Giorgos Kargas, Giuseppe R Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
Authors Nick D Bergkamp , Jeffrey R van Senten , Hendrik J Brink , Maarten P Bebelman , Jelle van den Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation
Habgood , Amanda L Tatler , Katalin Susztak , Matthew Palmer , Stefan Offermanns , Neil C Henderson , R Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- TIPE proteins control directed migration of human T cells by directing GPCR and lipid second messenger signaling
Authors Jiyeon Yu , Ali Zamani , Jason R Goldsmith , Zienab Etwebi , Chin Nien Lee , Youhai H Chen , Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Ovarian cancer G protein-coupled receptor 1 (OGR1) deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice
in Oncology and Immunology Ovarian cancer G protein-coupled receptor 1 (OGR1) deficiency exacerbates crystal GPR4 KO and OGR1 KO mice. After 10 days of high-oxalate intake and 4 days of recovery, renal crystal OGR1 deficiency, however, increases crystal deposition leading to impaired kidney function. Thus, OGR1 may be important to limit kidney crystal deposition, which might subsequently be relevant Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic target
. 1.09 ± 0.42, p < 0.001) and showed a positive correlation with immunostaining of protein in OSCC (r Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
Riley E Perszyk , Nicholas H Harbin , Jennifer Okalova , Suneela Ramineni , Stephen F Traynelis , John R Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Authors Charles H Williams , Leif R Neitzel , Jessica Cornell , Samantha Rea , Ian Mills , Maya S Silver Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers
- Full Agenda for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Salinas Read More 12:00 PM Session IV AGPCRs signaling in the nervous system Joseph Duman · Simeon R. The N-Terminal Fragment Of ADGRG6 Drives Proteolytic Processing, Trafficking And Signalling Simeon R.
- Ep 151 with Dr GPCR Board
My experience in basic research at several universities worldwide and early R&D at Novo Nordisk A/S allowed
