Search Results
22 items found for "Leif R Neitzel"
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Authors Charles H Williams , Leif R Neitzel , Jessica Cornell , Samantha Rea , Ian Mills , Maya S Silver
- Ep 96 with R. Scott Struthers
GPCR Podcast << Back to podcast list Scott Struthers R. R. Scott Struthers on the web LinkedIn Google Scholar Crinetics Radionetics Dr.
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
with decitabine (DAC) demonstrated initial safety and efficacy in patients with relapsed/refractory (R/ R) AML. The current study aimed to identify molecular predictors of response to ONV + DAC in R/R AML patients A total of 44 R/R AML patients were treated with ONV + DAC and considered evaluable for efficacy. PLK1 inhibition with ONV in combination with DAC could be a potential therapy in R/R AML patients, particularly
- Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis
bifunctional GLI transcription factors generate both GLI-activators (GLI-A) and GLI-repressors (GLI-R) The formation of GLI-A/GLI-R requires cilia. , and the ankyrin repeat protein ANKMY2 that direct cAMP/protein kinase-A signaling by cilia in GLI-R GLI-A formation only, or dual regulation of either lack of GLI-R or excess GLI-A formation. complex tissue-specific GLI-effector requirements in morphogenesis and point to tissue-specific GLI-R
- Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
in Axons Joseph Duman Bai1 Is A Novel Neuronal Substrate Of The Psychiatric Risk Kinase TNIK Simeon R. Kimberley Tolias Lab Bai1 Is A Novel Neuronal Substrate Of The Psychiatric Risk Kinase TNIK Simeon R. Mihaylov Abstract Only available for AGPCR 24 Attendees Authors & Affiliations "Flynn, Helen R.2, Sampedro-Castaneda Institute, UK 2Proteomics Science Technology Platform, The Francis Crick Institute, UK" About Simeon R. have recently also developed a strong interest in adhesion GPCRs and in particular, Bai1. " Simeon R.
- Ep 104 with Dr. Raul Gainetdinov
Raul Gainetdinov Raul R. Before SPBU, Raul R. In 2018-2020, Raul R.
- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
ARB1 and ARB2 correlated negatively CERAD Trail Marking A and B (R ≤ -0.26, p ≤ 0.043), while CHRM3 correlated positively with Chadler Fatigue Scale (R = 0.37, p = 0.0087).
- Ep 57 with Dr. Peter Robert Banks
These roles included management of PerkinElmer’s BioPharma R&D program and Chair of the company’s Scientific
- Ep 17 with Dr. Yamina Berchiche
Yamina Berchiche on the web D r.
- Ep 84 with Rosie Dawaliby
I have 10 years of experience in the development and management of R&D projects and teams in the field
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
Authors Quanbo Wang , Charles R Mackay Tags Gut microbiota , Western lifestyle diseases , portal vein
- Ep 95 with Chris Langmead
He also directs a collaborative neuroscience R&D program with Servier (France) and is the co-founder
- The landscape of cancer-rewired GPCR signaling axes
De Oliveira Rosa, Francesco Carli, Lauren Clubb, Lorenzo Amir Nemati Fard, Giorgos Kargas, Giuseppe R
- Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation
Habgood , Amanda L Tatler , Katalin Susztak , Matthew Palmer , Stefan Offermanns , Neil C Henderson , R
- Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic target
. 1.09 ± 0.42, p < 0.001) and showed a positive correlation with immunostaining of protein in OSCC (r
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
Riley E Perszyk , Nicholas H Harbin , Jennifer Okalova , Suneela Ramineni , Stephen F Traynelis , John R
- Full Agenda for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Salinas Read More 12:00 PM Session IV AGPCRs signaling in the nervous system Joseph Duman · Simeon R. ADGRF5/GPR116 receptor is a key regulator of lymphatic endothelial cell identity and function Simeon R.
- Ep 153 with Dr Jacek Mokrosiński
He works in a multidisciplinary Chemical Biology team based at the recently established US R&D hub in
- Ep 151 with Dr GPCR Board
My experience in basic research at several universities worldwide and early R&D at Novo Nordisk A/S allowed
- Plenary Lecture | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
β-arrestin-1 and CFTR at apical membrane of efferent ductulus to regulate the salt/water metabolism (eLife
- Investigating isoform switching in RHBDF2 and its role in neoplastic growth in breast cancer
Neither EGFR nor ERAD was found enriched.
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