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April 2022 Sosei Heptares Confirms Senior Leadership Changes to Drive the Company Through the Next Stage Sosei Group Corporation (“the Company”; TSE: 4565) today confirms that a series of Executive Management changes

Obesity-induced changes in human islet G protein-coupled receptor expression: Implications for metabolic

assays to monitor β-arrestin recruitment or signaling, and assays to monitor receptor conformational changes In particular, focus lies on the mechanism behind the techniques, and the specific advantages and challenges

and objectives: The concentrations of adrenocorticotropic hormone and cortisol in plasma, as well as changes pathways related to inhibitory Gi-mediated G protein-coupled receptor (Gi-GPCR) neurons and neuropeptide changes genes: Ciart, per2, per3, cry1, and cry2) were enriched in cortisol secretion and circadian rhythm changes Authors Hong Zeng , Li Cheng , De-Zhi Lu , Shuai Fan , Ke-Xin Wang , Li-Li Xu , Bin Cai , Mou-Wang Zhou

Immunofluorescence was used to detect the translocation changes of YAP to nucleus. Authors Xiaoyan Ding , Xiaoxia Li , Yanxia Jiang , Yujun Li , Hong Li , Lipeng Shang , Guilin Feng , Huhu Zhang , Ziyuan Xu , Lina Yang , Bing Li , Robert Chunhua Zhao Tags Autophagy , NSCLC , PKA-Hippo

Authors Shaohan Ma, Ruyue Li, Guangqi Li, Meng Wei, Bowei Li, Yongmei Li, Chunfang Ha Tags G protein-coupled