Search Results
61 items found for "Lin Tong"
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
Authors Juan Song , Miao Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin Song Tags Acute lung injury , Apoptosis , Cell-renewal , Inflammation , Regulator of G protein signaling
- GPR56: GPCR as a guardian against ferroptosis
Lin et al. demonstrated that GPR56, a G-protein-coupled receptor, can be activated by its agonist to
- The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer
Authors Pengfei Yan, Xi Lin, Lijie Wu, Lu Xu, Fei Li, Junlin Liu, Fei Xu Source Contribute to the GPCR
- GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway
Authors Yaoxin Gao, Weirong Zhan, Dandan Guo, Haizhen Lin, Muhammad Asad Farooq, Chenxu Jin, Li Zhang , Ying Zhou, Jie Yao, Yixin Duan, Cong He, Shuai Jiang, Wenzheng Jiang Tags DCs , GPR97 , Keratinocytes
- Ascitic Shear Stress Activates GPCRs and Downregulates Mucin 15 to Promote OvarianCancer Malignancy
Jackson, Ishwarya Venkata Narayanan, Fulei Wuchu, Minal Nenwani, Zachary Fischer, Alec Sunshine, Zequan Lin
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice
- GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis
Authors Jie Xiong , Yu-Ting Dai , Wen-Fang Wang , Hao Zhang , Chao-Fu Wang , Tong Yin , Shu Cheng , Hui-Juan Zhong , Shan-He Yu , Lu Jiang , Sheng-Yue Wang , Hai Fang , Rui-Hong Zhang , Yue Zhu , Hong-Mei Yi ,
- LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
Authors Jong Min Hong , Jin-Woo Lee , Dong-Seung Seen , Jae-Yeon Jeong , Won-Ki Huh Tags Cancer , Chemokine
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Hsi-Hsien Lin as summer intern twice, and finally joined the lab of Prof. Engel. This regimen has long lasting side-effects, including neuroendocrine and cognitive problems, and ~ 30%
- GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
cell motility. " Authors Yu Jin Lee , Kyeong Jin Shin , Hyun-Jun Jang , Jin-Sun Ryu , Chae Young Lee , Jong Hyuk Yoon , Jeong Kon Seo , Sabin Park , Semin Lee , A Reum Je , Yang Hoon Huh , Sun-Young Kong , Taejoon
- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
< GPCR News < GPCRs in Oncology and Immunology Severity of neurological long-COVID symptoms correlates The pathogenesis of Long-COVID is currently under heavy scrutiny and existing data on the role of auto-immune moderate SARS-CoV-2 infection up to 12 months prior to enrollment with (n = 72) or without (n = 58) Long-COVID Results: The prevalence and concentrations of evaluated autoantibodes were significantly higher in Long-COVID significantly higher number of patients with simultaneous detection of more than one autoantibody in Long-COVID
- RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment
Authors Peng Kong , Xu Wang , Ya-Kun Gao , Dan-Dan Zhang , Xiao-Fu Huang , Yu Song , Wen-Di Zhang , Rui-Juan
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
earlier transcriptomic analysis identified Urothelial Carcinoma Associated-1 (UCA1) as an LPA-stimulated long Srishti Kashyap , Kar-Ming Fung , Chao Xu , Resham Bhattacharya , Priyabrata Mukherjee , Ciro Isidoro , Yong Sang Song , Danny N Dhanasekaran Tags GPCR , High Grade Serous Ovarian Carcinoma , Let-7 miRNAs , Oncogenic
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
Authors Hao Shen, Jie Yuan, Dafeng Tong, Bingchen Chen, Enda Yu, Guanglei Chen, Cheng Peng, Wenjun Chang
- Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation
Authors Michael Trogdon, Kodye Abbott, Nadia Arang, Kathryn Lande, Navneet Kaur, Melinda Tong, Mathieu
- Ep 107 with Dr. Roger Sunahara
the crystal structure of the beta2-adrenergic receptor (beta2AR)-G protein complex, team effort with long question regarding the signaling differences in G protein splice forms, specifically the short and long Galpha-s(l), but not Galpha-s(s), regulates extracellularly regulated kinases (ERK), and that this long optimize its potential as a treatment for cocaine abuse, a debilitating disease that would require long-term
- Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3-L1 preadipocytes
Authors Zhenyu Yao, Jun Meng, Jing Long, Long Li, Weicong Qiu, Cairong Li, Jian V Zhang, Pei-Gen Ren
- Ep 86 with Nicole (Nicki) Perry-Hauser
My long-term research interests involve resolving signaling pathways downstream of aGPCRs and establishing
- Ep 22 with Dr. Kari Johnson
She is a neuropharmacologist with an interest in the long-term effects of alcohol abuse on neural circuits
- Ep 151 with Dr GPCR Board
The long-term goal of Dr. GPCR About Anne Marie Quinn "Anne Marie Quinn has a long and varied work experience in the biocomputing Prior to that, they obtained a Bachelor of Arts (B.A.) degree from California State University, Long
- Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy
Authors Yi Tang, Ye Tian, Chun-Xia Zhang, Guo-Tai Wang Tags G Protein-coupled receptors , Olfactory receptors
- G protein-coupled receptor-mediated signaling of immunomodulation in tumor progression
Authors Guang-Hong Qiu, Bin Yu, Mei Ma Tags GPCRs , cancer immune checkpoints , cancer immunotherapy
- Role and recent progress of P2Y12 receptor in cancer development
However, a new study suggests that long-term use of P2Y12R inhibitors may increase the risk of cancer
- GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy in Colorectal Cancer
cAMP/PKA/BNIP3L axis, thereby promoting the tumorigenesis and progression of CRC. " Authors Junwei Tang
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
We further show that these self-generated gradients can sustain the long-range guidance of DCs, adapt
- A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection
Authors Naina Gour , Hwan Mee Yong , Aishwarya Magesh , Aishwarya Atakkatan , Felipe Andrade , Stephane Lajoie , Xinzhong Dong Tags IFNγ , Mrgpra1 GPCR , NPFF , lung infection , neuropeptide FF , neutrophil
- Atypical Structure and Function of Typical Chemokine Receptors
Our laboratory has a long-standing interest in the way that NMDA receptors contribute to the symptoms
- Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer
Zhao , Vincent DiGiacomo , Mariola Ferreras-Gutierrez , Shiva Dastjerdi , Alain Ibáñez de Opakua , Jong-Chan