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47 items found for "Lipeng Shang"
- RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway
Immunofluorescence was used to detect the translocation changes of YAP to nucleus. Authors Xiaoyan Ding , Xiaoxia Li , Yanxia Jiang , Yujun Li , Hong Li , Lipeng Shang , Guilin Feng , Huhu Zhang , Ziyuan Xu , Lina Yang , Bing Li , Robert Chunhua Zhao Tags Autophagy , NSCLC , PKA-Hippo
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
Authors Amos Hong Pheng Loh , Min Thura , Abhishek Gupta , Sheng Hui Tan , Kelvin Kam Yew Kuan , Koon Hwee Ang , Khurshid Merchant , Kenneth Tou En Chang , Hui Yi Yon , Yong Chen , Mathew Hern Wang Cheng
- [Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]
Authors Y H Hu , L L Shang , S H Ge Source Contribute to the GPCR News Coming soon Become a Contributor
- Ep 107 with Dr. Roger Sunahara
structural work on the GPCR-G protein complexes have also revealed some unprecedented conformational changes Some of these changes are associated with G protein activation while the functional consequences of other structural changes remain elusive. have been heavily engaged in studies to address the functional role of these dramatic conformational changes
- Colorectal cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004-2018
We calculated the estimated annual percentage change (EAPC) with 95 % confidence intervals (95 % CI) increasing trends in CRC incidence rates from 2004 to 2018 (EAPC = 3.7; 95%CI: 0.4, 7.1), with the greatest changes Conclusion: The increasing trends in CRC rates in Golestan are largely driven by generational changes
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- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
HE staining, ELISA, and immunohistochemistry were used to evaluate pathological changes and the degree vitro, qRT‒PCR, immunofluorescence staining, and western blotting were used to determine the dynamic changes Compared with the control group, we found higher mortality, more pronounced body weight changes, more
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- Esophageal and gastric cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004 to 2018
The estimated annual percentage change (EAPC) with 95% confidence interval (95% CI) were calculated. The marked declines in EC incidence rates in Golestan relate to generational changes in its underlying
- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
ATP2A2 and ARID5B correlated with the GH change rate in the octreotide loading test, and WWC3, SERINC1 , and ZFAND3 correlated with the tumor volume change rate after somatostatin analog treatment.
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
and objectives: The concentrations of adrenocorticotropic hormone and cortisol in plasma, as well as changes pathways related to inhibitory Gi-mediated G protein-coupled receptor (Gi-GPCR) neurons and neuropeptide changes genes: Ciart, per2, per3, cry1, and cry2) were enriched in cortisol secretion and circadian rhythm changes
- Ep 135 with Dr. Katarzyna Marcinkiewicz
Ph.D. from Weill Cornell Graduate School of Medical Sciences in New York City, studying epigenetic changes
- Ep 06 with Dr. J. Silvio Gutkind
highlights how his past experience proves useful in current COVID times and potential benefits the changes
- Ep 120 with Brendan Wilkins
Since then, Brendan worked as a research assistant at the Victor Chang Cardiac Research Institute where
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
downstream cAMP measurement, tolerant RGS14-D137Y and RGS10-S64T and intolerant RGS10-K89M resulted in change that 3DMTR identified intolerant residues that overlap with cancer-linked mutations cause phenotypic changes
- Itaconate in host inflammation and defense
and defense Published date March 5, 2024 Abstract "Immune cells undergo rapid and extensive metabolic changes
- A journey from Duke to McGill along the dopamine circuit
Abstract Coming Soon About Bruno Giros "Bruno Giros' lab is dedicated to investigating how molecular changes
- Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
Umesh Kumar Dhawan , Mohammed Tayab Hussain , Praveen Singh , Karran Kiran Bhagat , Aarushi Singhal , Shani
- Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ
signalling, it would be of utmost importance to find out the regions undergoing histone modification changes
- Ep 148 with Dr Arthur Christopoulos
Lastly, they touched upon the global challenges of healthcare workforce growth, climate change, and emerging Lastly, they discussed the global challenges of healthcare workforce growth, climate change, and emerging The conversation highlighted ongoing challenges within universities, including resistance to change and
- Ep 149 with Dr Arthur Christopoulos
Lastly, they touched upon the global challenges of healthcare workforce growth, climate change, and emerging Lastly, they discussed the global challenges of healthcare workforce growth, climate change, and emerging The conversation highlighted ongoing challenges within universities, including resistance to change and
- High expression of GPR50 promotes the proliferation, migration and autophagy of hepatocellular carcinoma cells in vitro
Authors Weiming Zhao , Lingling Xi , Guoying Yu , Gaiping Wang , Cuifang Chang Source Contribute to the
- Atypical Structure and Function of Typical Chemokine Receptors
It plays an important role in the way that neurons wire together and change the strength of synaptic
- Dynamic Phosphoproteomics of BRS3 Activation Reveals the Hippo Signaling Pathway for Cell Migration
Authors Miao Guo , Yan Zhang , Lehao Wu , Ye Sheng , Jiaqi Zhao , Zeyuan Wang , Huiyu Wang , Lu Zhang
- Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis
Authors Chaoliang Li , Panrui Zhang , Yadong Xie , Shishan Wang , Meng Guo , Xiaowei Wei , Kaiguang Zhang , Dan Cao , Rongbin Zhou , Sheng Wang , Xinyang Song , Shu Zhu , Wen Pan Tags Enterococcus , IBD , ISCs
- GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis
Authors Jie Xiong , Yu-Ting Dai , Wen-Fang Wang , Hao Zhang , Chao-Fu Wang , Tong Yin , Shu Cheng , Hui-Juan Zhong , Shan-He Yu , Lu Jiang , Sheng-Yue Wang , Hai Fang , Rui-Hong Zhang , Yue Zhu , Hong-Mei Yi ,
- Ep 106 with Dr. Bruno Giros
Giros' lab investigates how molecular changes at the nerve synapse might impact integrated behavior and
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
Authors Hao Shen, Jie Yuan, Dafeng Tong, Bingchen Chen, Enda Yu, Guanglei Chen, Cheng Peng, Wenjun Chang