G-protein signaling activates the MAPK Fus3, which phosphorylates the RGS; however, the role of this RGS phosphorylation peaks early; the phospho-state of RGS controls its localization and influences MAPK

JoAnn Trejo's study 'identifies two deubiquitinases that regulate GPCR-p38 MAPK signaling and distinct Robert J Lefkowitz and team's study 'GPCR signal transduction: β-arrestin activates ERK MAPK.' Dr. You can find more information about them on the Live Talks page and mark your calendar HERE. receptor An siRNA library screen identifies CYLD and USP34 as deubiquitinases that regulate GPCR-p38 MAPK domains in the β2 -adrenergic receptor Signal transduction at GPCRs: Allosteric activation of the ERK MAPK

time of peak hypersensitivity implicate potential contributions of mitogen-activated protein kinase (MAPK development of 7α,25-OHC/GPR183-induced mechano-allodynia was associated with significant activation of MAPKs mechanistic insight into how GPR183 signaling in the spinal cord produces hypersensitivity through MAPK We found that 7α,25-OHC-induced allodynia is dependent on MAPK and NF-κB signaling pathways and results

hepatocellular carcinoma (HCC) HuH7 cells through the activation of AKT, p38 mitogen-activated protein kinase (MAPK phosphorylation of JNK without affecting the phosphorylation of epidermal growth factor receptor, AKT, p38 MAPK

protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK

M84 induced PAR-1 overexpression along with activating its downstream signaling effectors NF-κB and MAPK