GTPase activity and result in constitutive signaling, as occurs with the αqQ209L mutation in uveal melanoma

in situ visualization and quantification of SST2/SST5 dimerization in rat GH3 as well as in human melanoma

immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma

< GPCR News < GPCRs in Oncology and Immunology GPR4 in the pH-dependent migration of melanoma cells in microenvironment Published date December 23, 2022 Abstract Due to its high metastatic potential, malignant melanoma In melanoma as well as in other cancers, acidification of the tumor microenvironment (= TME, inverse Results indicate that GPR4 is involved in the migration of melanoma cells, especially in the tumor periphery Haubner , Joachim Wegener , Stephan Schreml Tags Boyden chamber , ECIS , GPR4 , impedance , malignant melanoma

Program < Back to schedule Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma

November 3rd / 4:20 PM Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma