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420 items found for "Metabolite GPCR"

  • A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages

    < GPCR News < GPCRs in Oncology and Immunology A disturbed metabolite-GPCR axis is associated with microbial In this scenario, metabolite-sensing G-protein coupled receptors (GPCRs), involved in several biological The aim of this study was to characterize the axis microbiota-metabolite-GPCR in intestinal surgical These patients also exhibited upregulated expression of most metabolite-sensing GPCRs analysed, which A better understanding of metabolite-sensing GPCRs, such as GPR109A, could establish their potential

  • High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases

    < GPCR News < GPCRs in Oncology and Immunology High Metabolite Concentrations in Portal Venous Blood Likely, many other metabolites will be present at high concentrations. News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions

    < GPCR News < GPCRs in Oncology and Immunology G protein-coupled receptors: A target for microbial metabolites Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells

    G-protein-coupled receptors (GPCRs) sense metabolites and can act as key mediators that translate gut Here, we show that GPR31, which is activated by the gut bacterial metabolite pyruvate, is specifically Our results highlight the role of GPCRs in tuning the human gut immune system according to local metabolic GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • Ep 105 with Annabelle Milner

    GPCR Podcast << Back to podcast list Annabelle Milner About Annabelle Milner Annabelle completed her placement at the Charles Perkins Centre in Sydney, investigating the effects of dietary carbohydrates on metabolic Annabelle’s Ph.D. work focuses on microbial-derived metabolites that signal through GPCRs expressed in GPCR Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

  • Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program map of thermogenic fat Vasiliki Karagiannakou GAIN Domain Dynamics And Its Relevance For Adhesion GPCR This made me pursue my higher education in the field of adhesion GPCRs. Emmanouil Kyrloglou on the web Adhesion GPCR Consortium LinkedIn A single cell GPCR map of thermogenic , located within the GPCR autoproteolysis inducing (GAIN) domain.

  • Ep 155 with Endocrine Metabolic GPCR Organizers

    GPCR Podcast << Back to podcast list Re-cap of Endocrine Metabolic GPCR 2024 with the Organizers About Aylin Hanyaloglu on the web LinkedIn Endocrine Metabolic GPCRs Researchgate Twitter Imperial College GPCRs. Her current research focuses on how metabolic GPCRs cross-talk and interact to regulate appetite and Caroline Gorvin on the web University of Birmingham Endocrine Metabolic GPCRs Society of Endocrinology

  • Dr. GPCR Community Presentation | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program GPCR Community Presentation Breaking Barriers: My Journey from Mexico to the Heart of the Dr. GPCR Ecosystem and beyond About Monserrat Avila Zozaya "My doctoral research was focused on investigating My research focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic GPCR < Previous Session Next Session >

  • Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program function The NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs Stephanie Häfner bioSens-All: A Multiparametric BRET-Based Platform for Comprehensive Profiling of adhesion GPCR Signaling Stephanie Häfner Abstract "G Protein-coupled receptors (GPCRs) are common drug targets, yet no approved ), with a particular focus on the adhesion GPCRs (aGPCRs) family.

  • Newsletter for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register AGPCR Newsletter Dr GPCR News Adhesion GPCR Consortium Newsletter - May 2024 Welcome to the 4th official Adhesion GPCR Consortium Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program.

  • [Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]

    < GPCR News < GPCRs in Oncology and Immunology [Inhibitory effect of downregulating G protein-coupled fibroblasts (GFs), thus to provide a foundation for delving into the role of G protein coupled receptor (GPCR The silencing efficiency of siGPRC5A was evaluated by real-time fluorescence quantitative PCR (RT-qPCR Authors Y H Hu , L L Shang , S H Ge Source Classified GPCR News More from Dr. GPCR Share < Previous Next >

  • Illuminating Functional Selectivity and Allosterism at GPCRs.

    Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Illuminating Functional Selectivity and Allosterism at GPCRs. GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

  • Session VIII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Adhesion GPCR Researcher associate, Netherlands Brain Bank" Cheng-Chih Hsiao on the web LinkedIn ReseachGate Adhesion GPCR Attendees About Douglas Tilley "Research in the Tilley laboratory focuses primarily upon aspects of GPCR function in the heart in an effort to uncover novel therapeutic directions for HF, including adhesion GPCRs

  • Plenary Lecture | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Plenary Lecture Identification and Functional Characterization of Adhesion GPCRs Our first main research aspect is the identification of endogenous ligand of GPCRs. Our third main research aspect is working mechanism of GPCR. hormones by GPCRs (Cell 2021, 2023, Nature 2023b), bile acids or its derivatives by GPCRs (Nature 2020

  • Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to Investigate Metabolic Disease Pathophysiology

    Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to About Joshua Gross "I am a neuropharmacologist interested in exploiting GPCR biased signaling to design , my lab will strive to develop novel GPCR pharmacotherapies that improve efficacy and minimize side GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by

  • Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program a key regulator of lymphatic endothelial cell identity and function Monserrat Avila Zozaya Adhesion GPCR My research focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic GPCR Adhesion GPCR BAI1/ADGRB1 can block IGF1R-mediated growth signalling, increase radiosensitivity Like many other aGPCRs, ADGRG6 undergoes autoproteolysis at the GPCR-autoproteolysis site (GPS) enclosed

  • The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells and boosts HIV-1 R5 replication

    < GPCR News < GPCRs in Oncology and Immunology The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells In this study, we looked for other GPCRs able to modify HIV-1 infection. Methods: We identified GPCRs expressed in primary CD4+CCR5+ T cells by multi-RT-qPCR. We studied GPCR dimerization by FRET technology. GPCR Share < Previous Next >

  • Metabolic crosstalk: Extracellular ATP and the tumor microenvironment in cancer progression and therapy

    < GPCR News < GPCRs in Oncology and Immunology Metabolic crosstalk: Extracellular ATP and the tumor microenvironment News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Mihaylov Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl I have recently also developed a strong interest in adhesion GPCRs and in particular, Bai1. " Simeon LinkedIn X (Twitter) Google Scholar Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR broadened my horizons with many more techniques in vivo and in vitro, with a main emphasis on the Adhesion GPCR

  • G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells

    < GPCR News < GPCRs in Oncology and Immunology G protein-coupled estrogen receptor (GPER)/GPR30 forms 2024 Abstract "G protein-coupled receptor 30 (GPR30), also named G protein-coupled estrogen receptor (GPER ), and the β1-adrenergic receptor (β1AR) are G protein-coupled receptors (GPCR) that are implicated in , GPR30 , PDZ domain , Protein complex , β(1)-adrenergic receptor Source Classified GPCR News More from GPCR Share < Previous Next >

  • Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Conformational And Functional Coupling Between Extracellular and Transmembrane Regions of a Holo-Adhesion GPCR Kordon Deorphanization Of The Adhesion GPCRs GPR110 and GPR116 Tingzhen Shen Self-Cleavage of GPR110 Activity In The G12/13 Pathway Júlia Rosell Endocytic Cues Determine the Signaling Profile of Adhesion GPCR Kordon on the web Araç Laboratory at UChicago Deorphanization Of The Adhesion GPCRs GPR110 and GPR116

  • GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis

    < GPCR News < GPCRs in Oncology and Immunology GPR37 expression as a prognostic marker in gliomas: a News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Session IX / Technology capsule: Light on aGPCR signaling and function | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Session IX / Technology capsule: Light on aGPCR signaling and function NovoiSMART - A new platform for GPCR antibody drug discovery Abstract Developing monoclonal antibody drugs against GPCRs and other multi-pass transmembrane targets, such as ion channels, remains a significant challenge Several case studies of GPCR and other multi-pass transmembrane targets are presented, including GPRC5D

  • Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice

    < GPCR News < GPCRs in Oncology and Immunology Regulator of G protein signaling protein 6 alleviates Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus

    < GPCR News < GPCRs in Oncology and Immunology CB2 stimulation of adipose resident ILC2s orchestrates News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling

    < GPCR News < GPCRs in Oncology and Immunology NPFF stimulates human ovarian cancer cell invasion by News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Session VIII * | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Langenhan Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong Kim The Adhesion GPCR GPR110 Deletion Hee-Yong Kim Abstract "G-protein coupled receptor 110 (ADGRF1, GPR110), an adhesion GPCR In this study, we report the discovery of an adhesion GPCR, named Cupidon, that regulates the switch I have a particular interest in understanding the premetazoan function of adhesion GPCRs."

  • Transcriptomic analysis of human cytomegalovirus to survey the indirect effects on renal transplant recipients

    < GPCR News < GPCRs in Oncology and Immunology Transcriptomic analysis of human cytomegalovirus to survey Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

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