June 2022 "Published on juin 22, 2022 On June 22, 2022, Michel Bouvier , Chief Executive Officer of IRIC

September 2022 Cell Surface Calcium-Sensing Receptor Heterodimers: Mutant Gene Dosage Affects Ca 2+ Sensing but Not G Protein Interaction "The calcium-sensing receptor is a homodimeric class C G protein-coupled receptor (GPCR) that senses extracellular Ca2+ (Ca2+o ) via a dimeric extracellular Venus flytrap (VFT

Celebrating Excellence: Hyoungjun Ham , Yamina Berchiche , Thomas Sakmar , Vladimir Katanaev , Helen Su

Congratulations to Domain Therapeutics for appointing Michael Gottlieb as Chairman and Dr. activates MAS-related G protein-coupled receptor MRGPRX2 and its putative mouse ortholog MRGPRB2 Metabolite-sensing 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated Signaling Networks June 25 - 29, 2024 | FENS

ligand bias of G protein-coupled receptors Antonios Drakopoulos , Peter Gmeiner , Davide Calebiro , Michael

. for their work on Conformational dynamics underlying atypical chemokine receptor 3 activation   Michael

October 2022 "Lysosomes coordinate cellular metabolism and growth upon sensing of essential nutrients Thus, LYCHOS functions in a lysosomal pathway for cholesterol sensing and couples cholesterol concentrations

These complex properties have driven the need for development of specialized tools that can sense neuropeptide

defining if agonists of GPR84 might find utility in conditions in which regulation of metabolism or energy sensing

In other brain regions, astrocytes sense diverse neurotransmitters and neuromodulators and, in turn,

The mammalian target of rapamycin (mTOR) senses upstream stimuli to regulate numerous cellular functions

clarifies sequence-function relationships and proposes functional molecular switches that encode agonist sensing

Acquired hypocalciuric hypercalcemia (AHH) is a rare disease caused by calcium-sensing receptor (CaSR

In this sense, G protein-coupled receptors (GPCRs) may be a good option to try to prolong our life while

Langenhan for his papers to highlight suggestions GAIN Domain Unfolding in Adhesion GPCRs Molecular Sensing Unveiling Mechanical Activation: GAIN Domain Unfolding and Dissociation in Adhesion GPCRs Molecular sensing

Proton-sensing G-protein coupled receptors are activated by acidic environments, but their role in fibrosis

implicated in Hc interaction with macrophages, including the ragulator complex (involved in nutrient stress sensing

expression of pattern recognition receptors, such as TLR2 and TLR4, provides platelets with the ability to sense

Molecular basis of proton-sensing by G protein-coupled receptors. bioRxiv .

atherosclerosis in vivo through inhibiting CREB-ALK5-mediated endothelial to mesenchymal transition Role of pH-sensing 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated Signaling Networks June 25 - 29, 2024 | FENS

Reviews, GPCRs, and more Olfactory Receptors as an Emerging Chemical Sensing Scaffold.

GPCR Activation and Signaling Atypical Chemokine Receptor 3 'Senses' CXC Chemokine Receptor 4 Activation

G protein-coupled receptors (GPCRs) are membrane-bound proteins that sense external stimuli and relay

Function Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing

associated with inhibition in germline G protein-coupled receptor CED-1 in Caenorhabditis elegans Calcium-sensing

receptors in vitro and in vivo GPCRs in Neuroscience Elucidating the activation mechanism of the proton-sensing

Every week, we send you the most relevant news, research, and advancements in the field. For Dr.

Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation.