News < GPCRs in Oncology and Immunology A disturbed metabolite-GPCR axis is associated with microbial dysbiosis Indeed, gut microbiota dysbiosis and metabolomic profile alterations, are hallmarks of IBD. The aim of this study was to characterize the axis microbiota-metabolite-GPCR in intestinal surgical Results showed that UC patients had a lower microbiota richness and bacterial load, with a higher proportion dysbiosis , Pro-inflammatory macrophages Source Contribute to the GPCR News Coming soon Become a Contributor

Oncology and Immunology High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota This model helps explain how the gut microbiome may be affecting peripheral immune cells, and consequently Authors Quanbo Wang , Charles R Mackay Tags Gut microbiota , Western lifestyle diseases , portal vein

Immunology G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain Recent studies have demonstrated that small-molecules from gut microbiota act as ligands for specific and metabolite cataloging with mechanistic studies for an improved understanding of gut microbiota-immune-brain Authors Gajender Aleti , Emily A Troyer , Suzi Hong Tags G protein-coupled receptors , Gut microbiota , Human-microbiota interactions , Immune system , Inflammation , Metabolites Source Contribute to the

colitis Published date May 21, 2024 Abstract "Inflammatory bowel disease (IBD) is characterized by dysbiosis of the gut microbiota and dysfunction of intestinal stem cells (ISCs).

I am now working at the Cleveland Clinic in Ohio, USA, studying the gut microbiome and its impact on

Claudia agreed, suggesting that the complexity of the gut microbiome is akin to a "complicated city vicus