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Our guest is Mark Schmeizl!

Mark Connor! Learn more about #GPCRs and life as an academic wearing different hats.

This week's highlight includes congrats to: Clementine E Philibert and Mikel Garcia-Marcos for their

Mikel Garcia-Marcos for their work on Get ready to sharpen your tools:A short guide to heterotrimeric Early-bird registration for premium Ecosystem members opens on July 31st, so mark your calendars and

Our previous Markov State Model (MSM) analysis of molecular dynamics simulations of membrane-embedded

their research on Time-resolved cryo-EM of G-protein activation by a GPCR Remi Janicot, Alex Luebbers, Mikel Garcia-Marcos, et al. for their work on Direct interrogation of context-dependent GPCR activity with

🎇 This Week’s Highlights: Congrats to: Remi Janicot , and Mikel Garcia-Marcos for their excellent

The conformational landscapes analyzed by Markov state models revealed that the overall conformation

June 2022 "June 15, 2022 06:30 AM EDT - In 2016, Abbie Celniker was promoted to partner at Third Rock Ventures as the firm raised just over $600 million for its fourth fund. Since then, Celniker has helped usher in an additional fund and headed a few startups as interim CEO. Coming on its 15th year, Third Rock Ventures announced its sixth fund today — and largest one by far — at a whopping $1.1 billion. Adding it all up, Third Rock has raised $3.8 billion since its inception. That money has gone to some 60 biotechs, much of it as early funding." Read more at the source #DrGPCR #GPCR #IndustryNews

., Garcia, K. C., Wess, J., & Kobilka, B. K. (2013). L., & Garcia, K. C. (2015). Structural biology.

., Garcia, K. C., von Zastrow, M., Inoue, A., & Kobilka, B. K. (2022).

GPCR University Last week marked the beginning of our first Dr.GPCR University course, 'Applying Pharmacology Class B1 G Protein-Coupled Receptors: Integrating Enhanced Sampling Molecular Dynamics Simulations and Markov

García-Nafría, and C.G.

Rivas-Santisteban , Ana Muñoz , Jaume Lillo , Iu Raïch , Ana Rodríguez-Pérez , Gemma Navarro , José Labandeira-García

García-Bea A, Miranda-Azpiazu P, Muguruza C, Marmolejo-Martinez-Artesero S, Diez-Alarcia R, Gabilondo García-Nafría J, Tate CG. Cryo-EM structures of GPCRs coupled to Gs, Gi and Go.

, requires less protein and has evolved to achieve resolutions comparable to X-ray crystallography (García-Nafría