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October 2022 Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable We found that Adgra1-/- male but not female mice exhibited elevated anxiety levels in the open field, mice. Finally, we found that PI3K/AKT/GSK-3β and MEK/ERK in amygdalae of Adgra1-deficient male mice were aberrantly activated when compared to wt male mice.

This week's highlight includes congrats to: Miles Thompson , Alexander Hauser , Caroline Gorvin ,   et

Miles Thompson, Alexander Hauser, Caroline Gorvin et al. for their research on GPCR gene variants and

I received my PhD in Biology at Arizona State University, where I worked in the lab of Miles Orchinik

Typical and atypical KOR agonists affect behavior differently in Male Rhesus Monkeys. Structural basis of bile acid receptor activation and Gs coupling. Mapping the GPCR Interactome in vivo in KI mice.

neurotransmission Nicole Perry-Hauser GPR110 modulates anxiety-like behaviors and memory function in mice GPCR GPR110 modulates anxiety-like behaviors and memory function in mice potentially through neuronal Anxiety and memory function were tested using both male and female mice at 5-6 month of age. compared to wildtype mice. The y-maze showed a significant sex by genotype interactions with GPR110 KO male mice having increased