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23 items found for "Mohammed Tayab Hussain"

Posts (17)

GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP
elicited an increase in intracellular calcium levels and phosphorylation of MAPKs, but in a delayed and sustained Interestingly, unlike PAR2-AP, GB83 and trypsin induced sustained receptor endocytosis and PAR2 colocalization
An overview of the compartmentalized GPCR Signaling: Relevance and Implications
In the endosomes, sustained G protein signaling has been associated with prolonged interactions between GPCRs and signaling effectors on endosomes supports multiple rounds of G protein activation, leading to sustained Activation of nuclear GPCRs, such as the metabotropic glutamate receptor 5 (mGluR5), can lead to sustained mechanisms underlying spatial bias in GPCR signaling involve both temporal and spatial components, sustained Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.
Crinetics Presents Clinical And Research Results At ENDO 2022
CRN04894 reduced both serum cortisol levels and 24-hour urine free cortisol excretion in the presence of sustained