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429 items found for "Molecular marker"
Posts (281)
- Molecular insights into psychedelic drug action
such applications, however, is a clearer understanding of how these drugs exert their effects at the molecular Here we review the current knowledge regarding the molecular details of psychedelic drug actions and
- Molecular targets of psychedelic-induced plasticity
August 2022 "Psychedelic research across different disciplines and biological levels is growing at a remarkably fast pace. In the prospect of a psychedelic drug becoming again an approved treatment, much of these efforts have been oriented toward exploring the relationship between the actual psychedelic effects and those manifestations of therapeutic interest. Considering the central role of the serotonin 5-HT2A receptor in the distinct effects of psychedelics in human psyche, neuropharmacology sits at the center of this debate and exploratory continuum. Here we discuss some of the most recent findings in human studies and contextualize them considering previous preclinical models studying phenomena related to synaptic plasticity. A special emphasis is placed on knowledge gaps, challenges, and limitations to evaluate the underpinnings of psychedelics' potential antidepressant action." Read more at the source #DrGPCR #GPCR #IndustryNews
- Molecular mechanism of allosteric modulation for the cannabinoid receptor CB1
Through (un)biased molecular dynamics simulations and mutagenesis experiments, we show that TM2 rearrangement
Other Pages (148)
- RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway
needed for treating drug-resistant non-small cell lung cancer (NSCLC) and overcoming drug resistance to molecular-targeted study aimed to identify the role of RGS20 in NSCLC prognosis and delineate associated cellular and molecular These insights support the role of RGS20 as a promising novel molecular marker and a target for future Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural and molecular
- miR-19a may function as a biomarker of oral squamous cell carcinoma (OSCC) by regulating the signaling pathway of miR-19a/GRK6/GPCRs/PKC in a Chinese population
and closely related thermosensory, systems in the vinegar fly Drosophila melanogaster to unravel the molecular By examining the expression of known and novel marker genes, we validated the identity of these clusters , synaptic vesicle cycle proteins, and cell adhesion molecules. Our findings provide valuable insights into the molecular basis of hygro- and thermosensation. Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural and molecular
- G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions
However, the underlying molecular mechanisms remain poorly understood. for deeper understanding of the inter-kingdom crosstalk at the molecular level. we elucidated their molecular interactions with specific human cell receptors, particularly expressed metabolite cataloging with mechanistic studies for an improved understanding of gut microbiota-immune-brain molecular Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural and molecular