NSCLC

2 items found for "NSCLC"

Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer
) METHODS: We explored the expression and prognosis of GPR37 in NSCLC through TCGA, GTEx, GEO, and GEPIA2 We detected the expression of GPR37 in NSCLC tissues and cell lines. Most importantly, we investigated whether GPR37 affects cisplatin-induced drug resistance in NSCLC. Furthermore, by conducting animal experiments, we assessed the impact of GPR37 on NSCLC and delved into Knockdown of GPR37 significantly inhibits the occurrence and development of NSCLC.
RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway
Novel therapeutic targets are urgently needed for treating drug-resistant non-small cell lung cancer (NSCLC Our study aimed to identify the role of RGS20 in NSCLC prognosis and delineate associated cellular and vivo experiments verified whether overexpression of RGS20 affect the proliferation and autophagy of NSCLC Conclusion: Our findings indicate that RGS20 drives NSCLC cell proliferation by triggering autophagy , Guilin Feng , Huhu Zhang , Ziyuan Xu , Lina Yang , Bing Li , Robert Chunhua Zhao Tags Autophagy , NSCLC