Search Results
32 items found for "Neuroendocrine immunomodulatory axis"
- Immunomodulatory Role of Neuropeptides in the Cornea
As research in this area expands, further insights are made into the role of neuropeptides and their immunomodulatory
- Endocannabinoid System in the Neuroendocrine Response to Lipopolysaccharide-induced Immune Challenge
component of the Gram-negative bacteria cell wall, disrupt not only the hypothalamic–pituitary–adrenal axis but also affects other endocrine systems such as the hypothalamic–pituitary–gonadal axis and the release
- Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and...
October 2022 Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and Further, pharmacological targeting of cGAS/STING-YAP axis exhibits the potential to alleviate liver and
- Signaling pathways activated by sea bass gonadotropin-inhibitory hormone peptides in COS-7 cells...
European sea bass, Dicentrarchus labrax, which exerted an inhibitory action on the brain-pituitary-gonadal axis GnIH peptides in teleosts, and represent a starting point for the study of interactions with multiple neuroendocrine
- Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand...
expressed in the central and peripheral nervous systems, where it regulates various processes including neuroendocrine
- 📰 GPCR Weekly News, September 25 to October 1, 2023
prognosis in nasopharyngeal carcinoma Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine
- 📰 GPCR Weekly News, January 15 to 21, 2024
progression or death by 72% as first-line treatment for patients with advanced gastroenteropancreatic neuroendocrine
- Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin...
This signaling axis was required for effective neutrophil-mediated skin immunity and microbiome homeostasis This study demonstrated the importance of epithelial-neutrophil signaling via the defensin-Mrgpra2 axis
- Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR
discovery programs in key therapeutic areas Kallyope, pioneers in drug discovery involving the gut-brain axis biopharmaceutical company, and New York City-based Kallyope, pioneers in drug discovery involving the gut-brain axis
- Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin ...
Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin Signaling Axis These data indicate that the AVP/arginine vasopressin receptor signaling axis represents a promising
- C3aR plays both sides in regulating resistance to bacterial infections
tissue specific responses during bacterial infections and emphasize the contribution of the C3a–C3aR axis
- Computational study of the conformational ensemble of CX3C chemokine receptor 1 (CX3CR1) and its...
Protein-Coupled Receptors (GPCR) superfamily, and its ligand fractalkine constitute an important biochemical axis
- Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota..
These data reposition key roles of the L cell-gut IEL GLP-1R axis, revealing mechanisms linking GLP-1R
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
exposures to common environmental pollutants result in long-term Reprogramming of hypothalamic-pituitary axis in mice GPCRs in Oncology and Immunology A disturbed metabolite-GPCR axis is associated with microbial
- Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent...
Together, these data reveal a shear-dependent signaling axis of PTK2, integrin αIIbβ3, and CIB1 in collagen
- TLR4 biased small molecule modulators
Small molecules biasedly modulating the TLR4 signaling axis not only provide probes to fine-tune receptor
- Effects of Small Molecule Ligands on ACKR3 Receptors
should allow us to better appreciate the unique roles of ACKR3 in the CXCL12/CXCR4/ACKR3-signaling axis
- Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024
CCR4Lc, CCR12a1, CCR12a2, and CCR12b) in largemouth bass (Micropterus salmoides) The pyruvate-GPR31 axis
- 📰 GPCR Weekly News, June 12 to 18, 2023
GPCRs in Oncology and Immunology The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer
- HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G 1/S cycle
ARRB1 plays a critical role in HBV-related HCC via modulating autophagy and the CDKN1B-CDK2-CCNE1-E2F1 axis
- 📰 GPCR Weekly News, January 16 to 22, 2023
The cannabinoid receptor 1 antagonist AM6545 stimulates the Akt-mTOR axis and in vivo muscle protein
- 📰 GPCR Weekly News, June 5 to 11, 2023
GPCRs in Immunology and Oncology The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer
- 📰 GPCR Weekly News, February 13 to 19, 2023
From outside to inside and back again: the lysophosphatidic acid-CCN axis in signal transduction.
- 📰 GPCR Weekly News, August 14 to 20, 2023
virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
- Biased Agonism at the GLP-1 Receptor: A Pathway to Improved Therapeutic Outcomes
agonists exhibit less interaction with ECL3, resulting in an open conformation of the TM6-ECL3-TM7 axis
- 📰 GPCR Weekly News, August 28 to September 3, 2023
GPCRs in Oncology and Immunology From outside to inside and back again: the lysophosphatidic acid-CCN axis
- 📰 GPCR Weekly News, June 26 to July 2, 2023
GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
- 📢 Early Bird Registration Ends Tomorrow! | Sep 16 - 22, 2024
GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis