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27 items found for "Neurotoxicity"
- Adenosine receptor signalling in Alzheimer's disease
Targeting these receptors preclinically can mitigate pathogenic β-amyloid and tau neurotoxicity whilst
- Adenosine receptor signalling in Alzheimer's disease
Targeting these receptors preclinically can mitigate pathogenic β-amyloid and tau neurotoxicity whilst
- Novel interaction between neurotrophic factor-α1/carboxypeptidase E and serotonin receptor, 5-HTR1E,
carboxypeptidase E, CPE) and human 5-HTR1E, a G protein-coupled serotonin receptor with no previously known neurological diminished the NF-α1/CPE-mediated protection of these neurons against oxidative stress and glutamate neurotoxicity-induced
- 📰 GPCR Weekly News, May 27 to June 2, 2024
molecular regulation between neuropeptide and neurotransmitter release GPCRs in Oncology and Immunology Neurotoxicity
- Applying Allosteric Modulator Pharmacology to Treat Dyskinesia and Other Movement Disorders with ...
molecule drugs known as allosteric modulators is being explored for treating central nervous system and neurologic
- Molecular basis for ligand modulation of the cannabinoid CB 1 receptor
of ligands for CB1 receptors have been developed as promising drug candidates for the treatment of neurological
- Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals
fundamental physiological functions, and dysregulation of dopaminergic transmission is associated with major neurological
- Orion Announces The Rapid Lead Optimization Of Ob-004 - A Ccr2 Antagonist
The CCL2/CCR2 pathway plays an important role in oncology, inflammatory, metabolic, and neurological
- 📰 GPCR Weekly News, June 24 to 30, 2024
by suppressing the MMP8-mediated antitumorigenic effects GPR56: A potential therapeutic target for neurological kisspeptin receptor Industry News Nxera Pharma Receives US$10 Million from AbbVie as Collaboration Targeting Neurological
- Karuna Therapeutics Announces Positive Results from Phase 3 EMERGENT-2 Trial of KarXT in...
company driven to create and deliver transformative medicines for people living with psychiatric and neurological
- Targeting mGluR2/3 for treatment of neurodegenerative and neuropsychiatric diseases
Therefore, mGluR2 and mGluR3 have been considered as potential drug targets for the treatment of many neurological
- Discovery of 3(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligand
S1R has been implicated in many neurological disorders such as anxiety, schizophrenia, and depression
- Lysine 101 in the CRAC Motif in Transmembrane Helix 2 Confers Cholesterol-Induced Thermal...
serotonin1A receptor is a crucial neurotransmitter receptor in the GPCR family involved in a multitude of neurological
- Latrophilin-1 drives neuron morphogenesis and shapes chemo- and mechanosensation-dependent ...
Adhesion GPCRs playing essential roles in the mammalian nervous system and are associated with severe neurological
- Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable to...
and exclusively expressed in the brain, suggesting that Adgra1 may be involved in the regulation of neurological
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
drug discovery Is the pharma community looking hard enough before trying to engage highly challenging neurology Neuroscience GPCR-Mediated Natural Products and Compounds: Potential Therapeutic Targets for the Treatment of Neurological
- 📰 GPCR Weekly News, October 9 to 15, 2023
Duke Novo Nordisk stops Ozempic kidney trial after early signs of success Sosei and PharmEnable extend neurological
- 📰 GPCR Weekly News - January 2 to 8, 2023
Development and Commercialization of Voyager’s GBA1 Program and Other Next-Generation Gene Therapies for Neurological
- Interacting binding insights and conformational consequences of the differential activity of...
plant Cannabis sativa, has displayed beneficial pharmacological effects in the treatment of several neurological
- 📰 GPCR Weekly News, April 1 to 7, 2024
immunity Industry News Neurosterix launches with $63M to Advance Allosteric Modulator Therapeutics for Neurological
- 📰 GPCR Weekly News, October 16 to 22, 2023
behavior Methods & Updates in GPCR Research Advancements in the use of xenopus oocytes for modelling neurological
- 📰 GPCR Weekly News, November 6 to November 12, 2023
Exscientia Business Update for Third Quarter 2023 Addex CEO Tim Dyer to Discuss Allosteric Modulators in Neurological
- 📰 GPCR Weekly News, September 4 to 10, 2023
Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines Severity of neurological
- VAMP2: a crucial player in the delivery of MOR to the synapse
pain perception and reward, the dysfunction in the MOR-SNARE complex interaction can lead to various neurological
- 📰 GPCR Weekly News, February 26 to March 3, 2024
through β1 adrenergic receptor GPCRs in Neuroscience Discovery of potential TAAR1 agonist targeting neurological
- Exciting GPCR Events for Next Year! + GPCR Weekly Rocket Launch ⦿ Oct 28 - Nov 3, 2024
development Chemokine CXCL13-CXCR5 signaling in neuroinflammation and pathogenesis of chronic pain and neurological
- GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024
setpoint in Drosophila Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic